Purpose To investigate whether serum anti-müllerian hormone (AMH), follicle stimulating hormone (FSH), or antral follicle count (AFC) are predictive for clinical pregnancy in women who underwent IVF cycles at the age of 35 and older Methods A total of 240 consecutive women who underwent IVF cycles at the age of 35 and older were enrolled in this crsoss-sectional study. Pregnant and nonpregnant women were compared. Results The median AMH level of pregnant women was higher than non-pregnant women [3.20 (0.63-9.60) vs 1.15 (0.01-14.90) ng/ml, p<0.001]. On logistic regression analysis, AMH was an independent predictor of clinical pregnancy rate (CPR) (OR 1.353; 95 % CI 1.141-1.605; P<0.001). After controlling for the other independent variables (the number of retrieved oocytes, AFC and age), the significant association between AMH and clinical pregnancy rate remained strong (OR 1.677; 95 % CI 1.216-2.311; p=0.002) on multivariate logistic regression analysis. Conclusions AMH is an effective measure of quantitative ovarian reserve and it can predict ovarian response to controlled stimulation for advanced age women. The CPR tends to increase as AMH increases.

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Objectives: The aim of this study was to investigate whether severe preeclampsia (SPE) affects intraocular pressure (IOP) and ocular perfusion pressure (OPP). Material and methods: This prospective and comparative study included 64 pregnant females, allocated into 2 groups as Group 1 (31 pregnant women with SPE) and Group 2 (33 normotensive pregnant women). IOP, systolic and diastolic blood pressure, OPP of all the subjects were measured after 20 weeks of gestation and prior to labor and medical therapy. Results: The mean IOP values in Group 1 were not significantly different from those of Group 2 (p = 0.528). The mean OPP values in Group 1 were significantly higher than those of Group 2 (p < 0.001). There was no significant correlation between IOP and OPP levels. No significant differences were determined between the groups in respect of age, gestational age body mass index (BMI) (p < 0.269, p < 0.219 and p < 0.556 respectively). The mean systolic and diastolic blood pressure values were statistically significantly higher in Group 1 than in Group 2 (p < 0.001 and p < 0.001). Conclusions: Although high IOP was expected in SPE patients, it was found to be constant. This could have been due to an increase in aqueous humor outflow because of changes occurring in angiogenic and anti-angiogenic factors in SPE.

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