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Analyzing antibiotic susceptibility pattern of uropathogens help to overcome the therapeutic difficulties created by the rising antimicrobial resistant bacteria and guides in choosing appropriate antibiotics. Hence, we aimed at evaluating the pathogens causing UTI and study their antibiogram. Midstream urine samples were collected, cultured and appropriate biochemical tests were performed for proper identification of urinary pathogens in BSMMU from January 2013 to December 2013. The most common isolated Gram negative uropathogens were Escherichia coli (63.93%) followed by Klebsiella pneumoniae (17.09%), other bacterial species, named Pseudomonas spp. Enterobacter Acinetobacter spp. Citrobacter spp Proteus spp. Morganella. Among Gram positive organism S. aureus S. saprophyticus S. agalectiae and Enterococci were found. Urinary tract infections were more prevalent in women than men (61.68% vs. 38.32%). High level of sensitivity was found to imipenem, amikacin, nitrofurantoin, ceftriaxone, gentamicin, cefuroxime in most of the isolates. Almost all the test organisms exhibited multiple antibiotic resistances. The high multiple antibiotics resistance identified makes it necessary for antibiotic susceptibility testing to be conducted prior to antibiotic(s) prescription.Bangladesh J Med Microbiol 2016; 10 (01): 22-26

This study was designed to find out the relationship between uses of different contraceptives and the prevalence of vaginal candidiasis. High vaginal swabs were obtained from 350 women in the age group of 15-45 years with vaginal discharge attending at Sir Salimullah Medical College Hospital, Dhaka, which comprised of 247 contraceptive users & 103 non-contraceptive users. A detailed clinical history and a thorough examination of all the cases were done. After making the clinical diagnosis, appropriate tests for diagnosing Candidiasis were done by using standard procedures. Of the 247 women of contraceptive users, Candida species was isolated in 140 (56.7%) cases compared to 32 (31.1%) from 103 non-contraceptive users (p value <0.001). Different species of Candida were isolated from 172 (49.1%) cases among 350 women of which C. albicans was found in 125 (72.7%) cases, C. glabrata in 29 (16.9%) cases, C. tropicalis in 13 (7.5%), and C. krusei in 5 (2.9%) cases. Among 173 oral contraceptive users, the isolation rate of Candida species was 120 (69.4%). This was followed by injectables (17, 12.2%) and IUCD (03, 2.1%) cases (p value <0.05). The study revealed a strong association between use of contraceptives and the prevalence of vaginal infection by Candida species of which C. albicans was the most common species (72.7%). Among all contraceptives, use of oral contraceptive pills (OCP) was found as the most common cause of vaginitis, next to which were injectables and IUCDs.Bangladesh J Med Microbiol 2007; 01 (02): 61-64

The aim of the present study was to examine the involvement of skin bacteria in the pathogenesis of keratosis. Skin swab of five different sites (palm, dorsum of the hand, chest, axilla and alar crease) from arsenic unexposed volunteer (n = 15), arsenic exposed (n = 15) and arsenicosis patients (n= 20) were collected for bacterial culture. The skin of arsenic unexposed volunteers contained Staphylococcus epidermidis and Bacillus spp. Chronic exposure to high concentration of arsenic through drinking water altered the skin bacterial pattern. The growth of Pseudomonas spp. increased in different sites of the skin. But in patient of arsenicosis, the skin of the palm shows the growth of Enterobacter spp.

Clinically diagnosed bronchial asthma patients comprising of new cases, on therapy or follow up were enrolled for this study to see if the new biological marker Eosinophilic cationic protein (ECP) can be used as a more precise marker to monitor therapy than the presently used conventional ones like FEV1% predicted, PEFR, and Circulating eosinophil (C.E) count. Out of 70 bronchial asthma patients, 30 intermittent, 4 mild persistent, 24 moderate persistent and 12 severe persistent asthma patients were included, while 45 cases were enrolled for follow up. Serum level of eosinophil granular protein, Eosinophilic cationic protein (ECP) was measured in relation to changes in their forced expiratory volume in 1st second (FEV1% predicted) and Circulating Eosinophil count (%) before and after therapy in 45 follow up patients on asthma therapy. In this study, it was observed that C.E count (%) and FEV1% predicted were not decreased significantly and serum eosinophilic cationic protein (ECP) decreased significantly (p<0.001) after asthma therapy. Thus, serum ECP level can be used as a biological marker than other conventionally used marker (FEV1, C.E count) to monitor therapeutic efficacy in bronchial asthma patients.