Summary The data on the predictors and prognosis of acute liver injury (ALI) among patients in coronavirus disease 2019 (COVID‐19) patients are limited. The aim of this study was to determine the prevalence, predictors and outcomes of ALI among patients with COVID‐19. A systematic review was conducted up to 10 June 2021. The relevant papers were searched from PubMed, Embase, Cochrane and Web of Science, and the data were analysed using a Z test. A total of 1331 papers were identified and 16 papers consisting of 1254 COVID‐19 with ALI and 4999 COVID‐19 without ALI were analysed. The cumulative prevalence of ALI among patients with COVID‐19 was 22.8%. Male and having low lymphocyte levels were more likely to be associated with ALI compared with female and having higher lymphocyte level, odds ratio (OR): 2.70; 95% confidence interval (CI): 2.03, 3.60 and mean difference (MD) −125; 95% CI: −207, −43, respectively. COVID‐19 patients with ALI had higher risk of developing severe COVID‐19 compared with those without ALI (OR: 3.61; 95% CI: 2.60, 5.02). Our findings may serve as the additional evaluation for the management of ALI in COVID‐19 patients.

Imunisasi merupakan upaya pencegahan penyakit, Cakupan imunisasi di Jawa Barat tahun 2017 sebesar 99,2%, sedangkan data cakupan imunsasi Dinas Kesehatan Indramayu (71,4%), di Puskesmas Kedungwungu 31,6% dan di Desa Purwajaya 28,3%. Penelitian ini berujuan untuk mengetahui faktor-faktor yang mempengaruhi kepatuhan ibu dalam pemberian imunisasi dasar pada balita di Desa Purwajaya Kecamatan Krangkeng tahun 2019. Desain penelitian ini adalah cross sectional yang dilaksanakan di Desa Purwajaya. Sampel penelitian 78 responden diambil secara accidental sampling. Pengumpulan data dilakukan dengan wawancara dan observasi. Analisis data secara univariat dan bivariat. Hasil analisis univariat diperoleh 55,1% imunisasi tidak lengkap, berpendidikan rendah 69,2%, berpengetahuan kurang 23,1%, keluarga yang tidak mendukung 53,8%, Hasil analisis bivariat diperoleh p-value pendidikan (0,704) tidak memiliki hubungan yang signifikan, pengetahuan (0,000) dan dukungan keluarga (0,000), memiliki hubungan yang signifikan dengan pemberian imunisasi dasar pada balita. Pengetahuan dan dukungan keluarga merupakan faktor yang mempengaruhi kelangkapan pemberian imunisasi dasar pada bayi, oleh karena itu diisarankan kepada petugas kesehatan agar meningkatkan promosi kesehatan terutama tentang imunisasi.

Background: The elderly population in Indonesia increased signifi cantly in the last two decades as the life expectancy increase from 66.7 years to 70.5 years with impact to the emergence of diseases in the elderly. One of them is degradation of cognitive function that may disrupt productivity, daily activities, and quality of life of the elderly. Adequate micronutrients intake may help in maintaining cognitive function.Objectives: To identify association between intake of micronutrients (vitamin B6, folate, vitamin C, and vitamin E) and cognitive function of the elderly at Among Yuswa Club of Banteng Baru, District of Sleman.Methods: This was an observational study with cross sectional design. Subjects were elderly people at Among Yuswa Club of Banteng Baru, District of Sleman. Data on cognitive function was obtained using the Mini Mental State Examination (MMSE) and intake of micronutrients were collected using Semi Qualitative Food Frequency Questionnaire (SQFFQ). The data was analysed by chi square and logistic regression tests.Results: The result showed statistically signifi cant association between cognitive function and intake of vitamin B6 (p=0.010; RP=2.514; 95%CI=1.133-5.575), vitamin C intake (p=0.011; RP=3.039; 95%CI=1.454-6.353) and vitamin E intake (p=0.021; RP=1.266; 95%CI=1.057-1.516); meanwhile folate intake has no signifi cant association with cognitive function (p>0.05).Conclusion: There were signifi cant associations between intake of vitamin B6, vitamin C and vitamin E with cognitive function. There was no signifi cant association found between intake of folate and cognitive function in the elderly.