The results suggest that tumor angiogenesis may play an important role in locally invasive aggressive biologic behavior of ameloblastoma and keratocystic odontogenic tumor. The angiogenesis could be a potent target for developing antiangiogenic therapeutic strategies, particularly in recurrent cases of odontogenic tumors.

Myofibroblast are essential for the integrity of human body by virtue of its role in wound healing and pathological organ remodeling. Myofibroblast is a universal cellular component in mammalian lesions, but not a typical component of normal untraumatized tissues. Therefore its presence in abundance in case of cancer is a matter of concern. Tumor microenvironment plays a pivotal role in tumor progression. These so called cancer associated fibroblast or myofibroblast are the major components and occur in stromal tissue during carcinogenesis processes. This study is a quantitative assessment of presence and distribution of myofibroblast in severe dysplasia, microinvasion and oral squamous cell carcinoma (OSCC).

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Aim: To evaluate the dentist’s knowledge, attitudes, and barriers towards silver diamine fluoride (SDF) in Tricity (Panchkula, Chandigarh, Mohali), India. Materials and Methods: A cross-sectional study was conducted using a selfadministered online questionnaire among 422 dental practitioners in Tricity (Panchkula, Chandigarh, Mohali), India from 25th August 2021 to 10th September 2021. The outcome variable of the study were knowledge, attitude, and barriers toward Silver Diamine Fluoride. A pretested questionnaire on a 5-point Likert scale was used. Results: A total of 55% of respondents strongly agreed and agreed that SDF is a good treatment option for primary teeth that are not in the esthetic zone. The barrier to its usage is being not readily available commercially, with the highest score of 48%. Conclusion: Increased efforts in SDF education may lead to greater use of this innovative approach to the management of cavitated carious lesions. The most cited barrier to the use of SDF is tooth staining associated with arresting caries.