recently, Afolabi et al. [5] reported a prevalence of 10.4% in a family practice population while Abioye-Kuteyi et al. [6] reported a 19.9% prevalence of undetected renal disease following screening of a rural population in Nigeria. A history of diabetes, hypertension (HTN) or cardiovascular disease confers the highest risks for developing CKD. [7] Other risk factors for CKD include hyperlipidemia, obesity, metabolic syndrome, human immunodeficiency virus infection, hepatitis C infection, positive family history of kidney disease and the use of potentially nephrotoxic drugs. The most common causes of CKD among Nigerians are glomerulonephritis, HTN, diabetes and obstructive
Metabolic syndrome and chronic kidney disease are major public health challenges. This study aimed at determining the prevalence of metabolic syndrome among chronic kidney disease patients. Methods: One hundred and sixty patients were enrolled. Glomerular filtration rates were estimated using the Cockcroft Gault formula. Metabolic syndrome was defined by the presence of 3 of the following: Central obesity (waist circumference of >102 cm in males or >88 cm in females); Hypertriglyceridemia >150 mg/dL, low HDL cholesterol (<40 mg/Dl in males and <50 mg/dL in females), Hypertension (>130/85mmHg), Fasting plasma glucose >100 mg/dL. Results: The overall prevalence of metabolic syndrome was 67.5%, CKD stage 5 had the highest prevalence (85.1%) (p = 0.165). Prevalence among diabetics was 82% (p <0.000). CKD stage and number of metabolic syndrome criteria positively correlated. Conclusion: approximately seven out of every 10 CKD patients had metabolic syndrome. It was more associated with advanced CKD. Diabetics compared to non-diabetics were 1.5 times more predisposed.
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