Biological activity of ellagic acid toward some pathogenic strains bacteria (Staphylococcus epidermatis, Bacillus cereus, Klebsiella pneumonia and Salmonella typhi) was studied. The investigation was conducted using plate-agar method. Gentamycin and streptomycin were used as standard drugs. The results show that the biological activity of ellagic acid was more effective than gentamycin and streptomycin.Also, the minimum effective dose of ellagic acid was found to be 0.15 mg|ml, while the minimum effective doses of gentamycin and streptomycin were 0.3 mg|ml and 2 mg|ml, respectively.
Infertility is the inability to conceive a child for more than one year. The present study indicates that the obesity associated with infertility. The aim of the study to determine follicle stimulating hormone, luteinizing hormone, testosterone hormone and prolactin levels. and cholesterol and triglyceride concentration in 2 nd inferetid women. This study was carried out at kamal al-samaarai hospital the data were collected from 95 secondary infertilial women were age between 16-45 years old and grouped them in to obese (n = 46) and non obese(n = 49). There was no significant difference between the two groups (p <0.05). Body mass index in Infertile obese women is slightly higher than non obese Infertile women which is statistically significant (P<0.001). However LH, TSH, cholesterol and triglyceride concentration in obese infertile women is significantly higher than non obese infertile women (p >0.05).The BMI was correlated positively with triglyceride in obese group while BMI was positive correlation highly significant with cholesterol in non obese group. Regression analysis revealed obese to be strongly associated with observed infertility. The elevated prolactin values in secondary infertile women clearly shows that there is a mechanism operating at the anterior pituitary level which shows an abnormal distribution of FSH and LH which may further explain the abnormal delay ovum maturation. This study also indicates obese associated with infertile more than non obese women.
Diabetes mellitus (DM) has been defined as a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. This study includes (84) subjects, their age ranged from (40 to 54) years. (20) subjects were healthy chosen as control group and (64) patients with type 2 diabetes mellitus were divided into three groups according to their type of anti diabetic therapy: (23) newly diagnosed group without therapy (Group1), (20) with metformin therapy (Group2) and (21) with metformin plus glibenclamide therapies (Group3). In the study lipid profile level were quantitatively determine by enzymatic methods, in addition to that fasting plasma glucose (FPG), Glycated hemoglobin (HbA1c%) and body mass index (BMI) were identified in the patients. There is significant increase in the level of lipid profile in patients group. Metformin alone produce a non-significant favorable effect on all lipids profile parameters while metformin plus glibenclamide showed a significant reduction in TC and LDL-C.
Polycystic ovarian syndrome (PCOS) is the most common and complex endocrine disorder affecting women in the reproductive age. The etiology of this syndrome is not completely known, so there is a developing proof that supports genetic basis, PCOS has a strong familial preference. This study was carried out to investigate the effect of body mass index (BMI) on ovarian hormones in women with PCOS and healthy women. Eighty-three women aged (17-40) years were divided into two groups for testing (BMI less than 25 and more than 25). Hormonal study of Luteinizing hormone (LH), Androgen, Estradiol (E 2 ) was done for each patient, the results of these hormones in patients compared with controls in both BMI groups with E 2 /T ratio showed a significant increase in patients women compared to controls in (p<0.05), While the results of Follicle stimulating hormone (FSH) and Total Testosterone (TT) showed an increase with not statistically significant. it has been concluded that the increase in BMI doesn"t show to have an opposite effect on FSH, Androgen, E 2 , and TT levels but the result of LH shows a highly significant increase in PCOS groups compared to controls when BMI˃25.
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