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Article Citation: Rani K, Memon AR, Akram M, Memon PJ. Obesity; association of serum vitamin d levels. Professional Med J 2016;23(6):665-668.

The Corona Virus is the pandemic all over the world. This viral infection attacked all over the world like as disaster of viral infection which causes morbidity and mortality in different regions of world like Asia, Europe, and Africa etc. The different countries control the spread and complications of covid-19 like Acute Respiratory Distress Syndrome in well manner. In second wave there was again out break of covid-19 some regions of world. Here we discuss the causes of reoccurrence and their preventive measurements from our break effects of Covid-19.

Aim: To determine the effects of vitamin E therapy in the management of dyslipidemia with combination of statin drugs and also to determine the efficacy of statin drugs with combination of vitamin E therapy. Methodology: This case control study was conducted at LUMHS Jamshoro. Total 200 patients of dyslipidemia with the age between 30 to 50 years were included with mentioned inclusion and exclusion criteria & aere divided in to two groups; control group who received only statin drugs for treatment of dyslipidemia and case control group who received station drugs along with Vitamin E 800 mgs in divided dose.The fasting blood glucose level was measured by glucose oxidase method while lipid profile parameters serum cholesterol, TG’s, Serum LDL levels were estimated byenzyme caloric method on Cobas auto analyzer (model c-111 ACN 435 GERMANY) while HbA1c% was estimated on microlab. The statistical analysis was done on SPSS version 21 by applying unpaired student t test and ANOVA. The p value less than 0.05 consider as significant. Results: Finally after treatment phase the Mean & SD value of serum cholesterol in control group was 209.13 ± 5.15 mg/dl while in case study group was 189.51 ± 6.11 mg/dl , serum TG’s levels in control group was 191.52 ± 7.83 mg/dl & case study group was 168.56 ± 7.81 mg/dl, serum LDL levels in control group was 120.44 ± 4.67 mg/dl & in case study group was 97.15 ± 5.76 mg/dl. All parameters of lipid profile significantly decline in case study group. Conclusion: This research concluded that there is strong positive impact of vitamin E along with statin therapy on the management of dyslipidemia and in prevention of cardiovascular complications. Keywords: Dyslipidemia, Vitamin E, Statin Drugs.

Introduction: Diabetes mellitus and its complications are spreading with increased rate in Asian population especially in Pakistan. Uncontrolled diabetes can lead to different micro vascular complications. Cataract is one of the complications of diabetes which may lead to lens degenerative changes and visual impairment. G6PD plays a vital role in preventive measurements from cataract development in normal population. Objectives: This Study was designed to estimate G6PD levels in diabetic without ocular manifestations & diabetic cataract population. Methodology: This cross sectional comparative study was done at the Department of Biochemistry LUMHS Jamshoro in collaboration with the Diabetic clinic, Institute of Ophthalmology & Diagnostic Research Laboratory LUMHS Jamshoro. 100 diagnosed subjects of diabetes were selected by Non-Probability type of sample technique with consent of subjects and they were divided in to two groups Group A as control 50 diabetic subjects with out ocular manifestation while Group B as case study group contain 50 subjects of diabetes with cataract. The fasting blood glucose level was estimated by Hexokinase Method while G6PD level was measured by kit method on SD Biosensor while HbA1c(% ) was estimated by TTAB methodology. The data was statistically analyzed by SPSS 21. Results: The mean level of G6PD in Group A was 15.63±2.45 u/Hb while in group B it was 9.01±3.11 u/G HB. This result finally concluded that there was significantly (<0.05) decline of G6PD diabetic cataract as compared with diabetic without cataract. Conclusion: This study concluded that there was significant decline in G6PD level in diabetic cataract. It is also concluded that the estimation of G6PD level in diabetic population will be beneficial to take early preventive measurements against diabetic vascular complications.