Latar belakang. Gangguan tidur dinilai dari gangguan dalam jumlah, kualitas, atau waktu tidur. Gangguan tidur banyak ditemukan pada remaja (73,4%), namun belum banyak dilakukan di Indonesia.Tujuan. Mengetahui prevalensi gangguan tidur pada remaja usia 12-15 tahun di SLTP “X”, Kelurahan Jati, Jakarta Timur.Metode. Studi potong lintang dilakukan terhadap 140 pelajar SLTPN 92 di Kelurahan Jati, Jakarta Timur pada bulan Mei 2009, dengan teknik stratified purposive sampling. Pengambilan data dilakukan menggunakan kuesioner Sleep Disturbance Scale for Children (SDSC) yang diisi secara self-administered oleh orang tua beserta anak di rumah.Hasil. Prevalensi gangguan tidur didapatkan 62,9%, dengan gangguan transisi bangun-tidur sebagai jenis gangguan yang paling sering ditemui. Separuh subjek memiliki perbedaan waktu bangun antara hari sekolah dengan hari libur, 72,9% memiliki perbedaan waktu tidur yang tidak signifikan. Separuh subjek tidur cukup selama hari sekolah, dan 65% di hari libur. Aktivitas yang menenangkan sebelum tidur dilakukan oleh 73,6% subjek. Uji kemaknaan menunjukkan hubungan antara gangguan tidur dengan durasi tidur di hari sekolah dan aktivitas di tempat tidur (p<0,05). Tidak ada hubungan antara perbedaan waktu bangun atau tidur hari sekolah dengan hari libur, durasi tidur di hari libur, kebiasaan konsumsi minuman berkafein, dan lingkungan dengan gangguan tidur (p<0,05).Kesimpulan. Gangguan tidur banyak ditemukan pada remaja usia 12-15 tahun. Sleep Disturbance Scale for Children dapat digunakan sebagai uji tapis dalam mendeteksi gangguan tidur pada remaja
Metaiodobenzylguanidine (MIBG) scans are sensitive testing tools for neuroblastoma. Persistent positive MIBG scans in patients with stage 3 neuroblastoma have previously been found to indicate maturation rather than regression. We assessed the significance of this finding in stage 4 neuroblastoma in the present study. Fifteen consecutive pediatric patients with stage 4 neuroblastoma treated between 2004 and 2014 at the Kagoshima University Hospital were retrospectively examined. Treatment involved a combination of multiagent chemotherapy, resection, autologous peripheral blood stem cell transplantation (PBSCT), radiotherapy, and maintenance therapy with retinoic acid. The MIBG uptake in each patient during treatment was assessed using a Curie score. The 5-year event-free and overall survival rates in 15 patients were 38.9% and 58.7%, respectively. Four patients with persistent positive MIBG scans who underwent autologous PBSCT but experienced decreased I-MIBG uptake during the clinical course survived without progression, and their event-free survival (EFS) was significantly superior to that of patients who showed negative MIBG scans after PBSCT (5-year EFS rate: 18.2%, p = 0.0176). Therefore, persistent positive MIBG scans with gradually decreased uptake after PBSCT do not always indicate neuroblastoma progression, and may instead indicate tumor maturation in some selected cases, if not all cases, of stage 4 neuroblastoma.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.