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Macroporous polymer supported nanoparticles of copper(I) iodide catalyst and macroporous polymer supported azide reagent were used to simplify the synthesis of 1,4-disubstituted-1H-1,2,3-triazoles from various benzyl halides following the green chemistry principles. This new one-pot protocol facilitates the workup of the reaction and provides the products in short times and at high yields. Heterogeneous catalyst and reagent can be reloaded and reused at least for 5 runs without significant decrease in the yields.Electronic supplementary materialThe online version of this article (doi:10.1186/2193-1801-2-64) contains supplementary material, which is available to authorized users.

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Herein, a new application of an ionic liquid containing copper (I), ([Cu(Im 12 ) 2 ]CuCl 2 ), is introduced. This ionic liquid was used as an efficient catalyst for the click cyclization between organic azides and terminal alkynes in various solvents. Then, the mixture of [bmim]BF 4 /[Cu(Im 12 ) 2 ]CuCl 2 was used as a green catalytic medium for the multicomponent click synthesis of 1,4-disubstituted-1H-1,2,3-triazoles from a-halo ketones. The reactions were performed efficiently in this mixture and excellent yields were obtained in all cases. This catalytic reaction medium was recycled five times without significant loss of activity.ß 2013 Published by Elsevier Masson SAS on behalf of Acade ´mie des sciences.