Introduction: Prediabetes is a condition that will develop into type 2 Diabetes Mellitus (DMT2) within 3-5 years. Glycaemic control is the primary intervention in long-term management, so structured education with appropriate and sustainable media is needed using mobile health technology. Objectives: The development of the "Melpredia" application based on an android application as a media for health promotion and its effect on HbA1c glycaemic control and self-care management. Methods: The Research type was Research and Development (R&D), and model testing using Quasi-experiments with pre-test post-test control group design was carried out for three months from January to April 2021. The purposive sampling technique consisted of 15 intervention groups and 15 control groups. The data were tested using Paired t-test and an independent t-test. The research instrument used by application "Melpredia." Results: The Android-based Melpredia application obtained a percentage of 89% (Fair) and the feasibility test for material aspects with a percentage of 90% (excellent). Using the Melpredia application has the effect of Prediabetes Self-Management Education based on an android application on HbA1c levels of 5.927 ± 0.1831 in people with prediabetes than conventional health promotion (p = 0.001). Conclusions: Application "Melpredia" android based and can effectively improve the HbA1c levels and self-care management of prediabetes in preventing diabetes mellitus by utilizing educational menu, meal planning, physical activity, and reminders use applications. "Melpredia" is more effective than conventional.

To evaluate the effectiveness of aerobic training on pain in Rheumatoid arthritis. Methods Asystematic literature search was carried out using the Pubmed, Embase, and Cochrane databases untilNovember 2016 and abstractly presented at a scientific meeting of rheumatology for 3 years. Randomizedcontrolled trials (RCTs) comparing resistance exercise-based therapy with interventions withoutresistance exercise for RA patients' treatment were included. Six literature studies, including 547 patients,met the study inclusion criteria. Patient characteristics and exercise did not affect the outcome. Subgroupanalysis revealed a trend toward higher effectiveness associated with high-intensity programs. There isevidence with a low risk of bias that an aerobic exercise program effectively reduces fatigue amongpatients with RA, especially in the short term. An RCT should be performed in patients with RA who areselected for fatigue to strengthen the evidence.

Background: Exclusive breastfeeding is a concrete effort to obtain a good growth and development for a baby, because breast milk contains all the essential nutrients needed for baby's growth and contains antibodies (colostrum) for the baby's immune system. Based on data sourced from the Directorate General, data obtained for coverage of breastfeeding  in 2015 in Indonesia amounted to 55.7%. Data from the health profile of Kota Tangerang in 2015 amounted to 67.36%, still not reaching the target of 80%. Research Purposes: Analyzing factors that related to the success of exclusive breastfeeding in an infants aged 7 - 12 months in Cipondoh Health Center, Tangerang City. Research Methods: This research uses descriptive quantitative method with cross sectional approach.  Hypothesis testing used chi-square, odds ratio (OR) and multivariate logistic regression analysis. Subjects of all breastfeeding mothers with infants aged 7-12 months who met the inclusion and exclusion criteria, the sample size was 90 respondents with an accidental sampling technique. Result:  Analysis of factors that have a statistically significant relationship with the success of exclusive breastfeeding is mother’s knowledge (p =0.016; OR=17,172; 95%CI; 1,704-173,000). Meanwhile, the relationship between factors of initiation of early breastfeeding, age, education, employment, parity, husband's support, health personnel support and the attitude of mothers with the success of exclusive breastfeeding is not statistically significant. Conclusions and Suggestions: Promotive efforts need to be done on mothers before pregnancy and families about the importance of breast milk. The targets of counseling are health workers, health cadres and the community.

Background: Diabetes Mellitus is one of the risk factors for COVID-19. This causes the morbidity and severity of COVID-19 patients to be higher in patients with diabetes. Objectivity: This study aimed to determine the effectiveness of treatment therapy for COVID-19 patients with comorbid diabetes at the South Tangerang City General Hospital. Material and methods: This study used a descriptive design with a quantitative approach and retrospective data collection. Sampling was done by Total Sampling with a total sample of 127 patients from 234 patients. Result: The characteristics of COVID-19 patients with comorbid diabetes were dominated by the male gender (55.1%), with an age range of 46-55 years (38.6%), high school education (43.3%), and have a private employee type of work (55.1%). The symptoms of COVID-19 patients with comorbid diabetes were cough (89.8%), with a length of stay for patients 7–14 days (72.4%).Treatment for COVID-19 with comorbid diabetes was antibiotics azithromycin (26.0%), antiviral remdesivir (62.2%), methylprednisolone (73.2%), acetylcysteine (85.0%), vitamin C (89.8%), and the antidiabetic group that is often used is insulin novorapid (41.7%). Conclusion: The results of laboratory examinations showed that COVID-19 treatment therapy is effective in reducing the amount of virus in the blood, which is indicated by an increase in the PCR value (p-value <0.001), lowering blood sugar levels (which is characterized by a decrease in blood sugar levels when (p-value <0.001) ), and reduce hypercoagulation which is characterized by a reduction in the value of D-dimer (p-value < 0.005).