No abstract

The safety of monosodium glutamate (MSG) usage has generated much controversy locally and globally. MSG is known to affect the structure and function of male reproductive system as well as fertility. The aim of the present work was to study the toxic effect of MSG on reproductive system of adult male albino rats and to determine the possibility to reverse this effect using curcumin and propolis. Seventy sexually mature male albino rats were used for this study and divided into 7 groups. The first 3 were control groups administered (distelled water, curcumin, and propolis), the 4th group was the experimental and administered MSG at a dose of 4 g/kg body weight for 6ws, the 5 th and 6 th groups, MSG was co-administered with curcumin or propolis at the doses of 10 mg, and 50 mg/kg body weight respectively and the 7 th group received combination of MSG, curcumin and propolis. It was found that MSG has adverse impacts on male rat reproduction including decrease testicular weight, with histological structure alternation, decrease sperm count and plasma level of testosterone and luteinizing hormone (LH). Coadministration of curcumin and propolis either separately or combined ameliorate these effects where testicular weight and structure of seminiferous tubules with their lumens full of sperms were regained compared to MSG treated animals. Sperm count; testosterone and LH levels were improved.

Aluminum phosphide (AlP) poisoning is a major problem, accounting for many Emergency Unit visits and hospitalization with increasing incidence of AlP toxicity in the last few years. In spite of the progress achieved in the field of toxicology and associated therapies, AlP is still responsible for a high rate of mortality due to the rapid onset of life-threatening symptoms, ineffective treatment and inadequate data on the efficacy of therapeutic interventions. AlP poisoning is a serious medical emergency demanding early and adequate management. In this prospective study of AlP toxicity, 44 patients admitted to emergency unit of Assiut university hospital in the period from 1st January to 30th June 2016 were included. There were 28 males (68.2%) and 16 females (31.8%). The majority of the cases were in the age group from 21 to 30 years (n=28, 54.6%). Thirty-six (81.8%) of admitted patients were from rural areas. Suicidal intake was the main mode of toxicity in 81.8% of cases. About 41% of the cases were shocked at their presentation and had metabolic acidosis. The mortality rate was 45.5%. The incidence of death in patients treated with N-acetyl cysteine to the incidence of death in non-treated patients was 1:12. AlP poisoning needs more attention due to associated fatality, the absence of an antidote, and a high number of youth victims. Supportive measures are vital in these patients. N-acetyl cysteine has a protective effect. 1211 patients have prompted the use of NAC as a therapeutic measure to replenish the glutathione. NAC also improved the hepatic manifestations and prevented hepatic necrosis. The NAC also delayed the mortality latency time [9]. This study was conducted to evaluate AlP toxicity among cases admitted to emergency unit of Assiut University Hospital and to prove the role of N-acetyl cysteine and adequate supportive measures in AlP management. 2. Methodology A descriptive cross-sectional (prospective) study was conducted on cases of AlP toxicity admitted to Assiut University Hospital emergency unit during the period from 1st

Abd-El-hameed et al ... differences, both osteometric and morphological, between the sexes of a particular racial phenotype and population (Steyn and Iscan, 1998). Original attempts to determine the sex were made for those bones of the pelvis and the skull with the idea that they are the best indicators of the gender. It is thought that, to some extent, the shape of the pelvis may correlate with that of the INTRODUCTlON Sex determination of unknown skeletal material is one of the most vital determinations made by forensic anthropologists (Patriquin et al., 2005). It is widely recognized that skeletal characteristics vary among populations, thus each population should have specific standards to optimize the accuracy of identification (Iscan, 2005). Numerous studies had focused on the

Intake of folic acid can protect the neonatal striatal tissue against iron-induced oxidative stress damage.