Objective: The aim of this study was to analyze the in vitro effect of White Wine Vinegar (WWV) on surface properties of removable partial dentures' (RPD) components. Methods: Thirty specimens of one artificial teeth and a slab of cobalt-chromium alloy for RPDs were prepared. Specimens were distributed randomly in 3 groups (n=10): distilled water (negative control), WWV and CoregaTabs® (commercial control). Before and after immersion regimens, the analyses undertaken were colour stability assessed using spectrophotometer, mean roughness surveyed by perfilometry, mass variation using an analytical balance and surface composition assessed by Raman micro-spectroscopy. The data were statistically analyzed by repeated-measures ANOVA and Tukey test (p<0.05). Results: No statistically significant differences were observed between the treatments on roughness and colour change. Distilled water increased the weight of specimens whilst CoregaTabs and WWV reduced significantly the mass (p<0.05). In the Raman analysis, reduction of Co-Cr peak at 470 cm -1 was detected after immersion in distilled water and CoregaTabs, demonstrating signs of alloy degradation. Peak at 2430 cm -1 after immersion in distilled water was observed. Conclusion: WWV at 30 vol % is a promising low-cost alternative for the daily cleaning of removable dentures without altering surface properties and composition of removable partial denture components.

This study has shown that propolis is a promising bioactive component in dental products, especially for use in Cariology and Periodontology. Although there has been significant progress in applications of propolis, the field of dental products is still a growing area and it is important to encourage innovation and development of new products incorporating propolis based on knowledge of its composition and therapeutic properties.

Background: Copaiba oil-resin has been widely used and is especially found in neotropical regions, for which several pharmacological activities have been documented over the years. Prospective studies in intellectual property banks are important to increase competitiveness and thus generate new products in various research areas. Objective: A prospective study was carried out on patents of products containing copaiba oil-resin for dental use in intellectual property banks. Methods: The research was conducted with patent searches in six intellectual property banks of the world. Relevant information about the invention in the patent document was collected, processed and described. Results: The search found 9 patents using copaiba resin oil-resin in dental products. The National Institute of Industrial Property (INPI-Brazil) had the highest number of deposits (5), followed by Espacenet (2) and Free Patents (2). C. Langsdorffii was highlighted as the most widely used species in the products and deposits of vehicles in formulations (3). All the patents in the search are A61K code for medical, dental or hygienic purposes. Conclusion: Most of the found patents are related to the area of Microbiology, specifically with application in Cariology. Brazil is represented by the INPI and presented the highest number of patent applications when compared to other intellectual property banks.

The use of psychoactive substances is an ancient fact in human history that has become a public health problem. Recognizing the severity of oral problems related to drug abuse and in view of the importance of the contribution of Dentistry in this theme, it became pertinent to perform a literature review on oral manifestations resulting from drug use. A literature review of articles published between 1991 and 2019 was performed, mainly through MEDLINE and LILACS, using as descriptors "oral manifestations" , "drugs of abuse" , "oral disorders" . We selected 41 articles related to the theme. There was a high prevalence of oral lesions among drug users in relation to the general population. Among the most frequent oral manifestations are caries, periodontitis, xerostomia, leukoplakia. The abuse of drugs can cause the most diverse damages to the oral health. Dental surgeons, when aware of the oral manifestation / drug abuse relationship, can play an active role in identifying and treating drug addicts.

Purpose. This study aimed to evaluate reports of patents for oral care formulations, based on Camellia sinensis (C. sinensis), deposited and granted in intellectual property banks. Methods. A survey was conducted through collection, treatment, and analysis of extracted information from patent reports selected. The documentary research was conducted in January 2021 on formulations with C. sinensis for dental applications, including since the first patent deposits until the current time. The risk of bias of clinical trials with these formulations was analyzed to verify the scientific evidence. The data extracted represent the distribution of the number of patents by banks, annual evolution of patent deposits, applicant of patents by country, distribution of patents according to International Patent Classification codes, and the types of patented products. Results. Data and information from 20 selected patents were extracted. The United States Patent and Trademark Office (USPTO) and World Intellectual Property Organization (WIPO) were the banks with the largest number of patents for products/formulations with C. sinensis for oral care applications with 7 (35%) and 6 (30%) patent registrations, respectively. Other banks did not provide patents related to the search. Patents of compositions were the largest with 14 filings, and the remainder of formulations are represented specially by mouthwashes and toothpastes. As for clinical application, 18 patents were filed as products with antimicrobial and antibiofilm action, while 2 patents are directed to the treatment of xerostomia. In general, the aspects of the studies of clinical efficacy pointed to a low risk of bias. Conclusion. The study pointed out a small number of products protected by patents for Camellia sinensis for oral care indication, highlighting mainly mouthwash compositions and formulations. In the methodological parameters of clinical trials carried out with the formulations, the majority pointed out a low risk of bias.