Herein we report the syntheses and characterization of two novel CdII-based metal–organic frameworks (MOFs) with the formulae: [{Cd(INH)(hpdia)}·3H2O]α (Cd-MOF-1) and [{Cd(INH)(bdc)}·DMF]α (Cd-MOF-2) (INH = isoniazid, hpdia = 5-(4-hydroxyphenylazo)isophthalic acid), H2bdc...

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Accessing homogenous glycoconjugates is of significance for assessing their biophysical activities and sometimes as vaccine candidate. Synthesis of glycoconjugates involves two species of which, glycosyl donor plays pivotal role in controlling the outcome of the glycosylation. Recently discovered alkynyl glycosyl carbonate donors possess self‐stability, high reactivity, and fast reaction time (15–30 min) when activated with [Au]/[Ag]‐catalysts. Herein, we report metal free conditions for the activation of the same alkynyl glycosyl carbonate donors using I2/TMSOTf in stoichiometric quantities. Extrusion product was characterized to be the vinylidene iodide by single crystal X‐ray analysis. The reaction conditions were illustrated to be suitable for synthesis of various glycosides, purine/pyrimidine nucleosides and a pentasaccharide repeating unit of Klebsiella pneumoniae (O‐3‐antigen).

Naphthalimide-hydroxyquinoline based conjugates (NQ1 and NQ2) were synthesized for the detection of nitroaromatics in HEPES buffer/DMSO (9/1, v/v, pH = 7.4) and Fe 3 + /Pd 2 + in CH 3 CN solvent. The NQ1 and NQ2 were characterized using NMR ( 1 H, 13 C, COSY) and IR spectroscopies. Theoretical studies revealed that 8-HQ moiety in NQ1 and NQ2 placed at orthogonal position with respect to naphthalimide core to minimize steric crowding. The energy gap between HOMO and LUMO for NQ1 and NQ2 were found to be À 3.1 eV. The emission spectrum of NQ1 and NQ2 showed decrease in the emission intensity at 450 nm upon addition of picric acid (PA) and trinitrotoluene (TNT) whereas addition of 2-nitroaniline caused quenching with concomitant red-shift of the emission band in 90 % HEPES buffer-DMSO. The detection limit of NQ1 for PA, TNT and 2-NA detection was calculated as 8.7 × 10 À 6 M, 2.2 × 10 À 5 M and 1.8 × 10 À 5 M. The complexation of NQ1 with PA, TNT and 2-NA was further supported by Job's plot, dynamic light scattering studies and NMR titrations. We successfully utilized NQ1 and NQ2 for the detection of PA, TNT and 2-NA in real soil samples with excellent recovery. NQ1 also showed quenching of the emission intensity at 450 nm upon addition of Fe 3 + and Pd 2 + ions in CH 3 CN. Thus, NQ1 showed solvent-dependent dual chemosensor type behavior. The functioning of NOR gate has been achieved using Fe 3 + /NACs with NQ1.