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Thing. In recent years, the importance of sports in improving the health of the population by involving people in physical education has increased. However, sports of the highest achievements are associated with the risk of occupational diseases. Physical and emotional stress of athletes can lead to impaired health. Dental diseases are also common in people involved in sports. In domestic and foreign literature, athletes describe bruxism, occlusal disorders, periodontal disease, tooth abrasion. Of particular interest are injuries of hard tissues of the teeth of athletes in connection with their highest prevalence, ineffectiveness of treatment and prevention. The goal is on the basis of a clinical and laboratory study of the state of hard tooth tissues in athletes, to develop and justify the tactics of complex treatment, prevention of diseases of hard tooth tissues. Methodology. All participants underwent a comprehensive dental examination, which included the main research methods (determination of complaints, medical history, external examination, examination of the oral cavity, detection of diseases of hard tissues of the teeth, malocclusion) and additional (X-ray examination, “hamburg testing”, diagnosis of T-scan, assessment of oral fluid indices, cytological examination of buccal epithelium, electrometry of hard tissues of teeth, assessment of resistance of hard tissues of teeth). Results. Based on the results, we developed a new treatment-and-prophylactic toothpaste based on Silivatit organosilicon glycerogel hydrogel with the addition of nanostructured hydroxyapatite. Its biocompatibility, remineralizing and anti-inflammatory activity are proved, and clinical efficacy in athletes with diseases of hard tissues of the teeth is confirmed. The tactics of the complex treatment and prevention of diseases of hard tooth tissues in athletes based on the differentiated choice of filling materials have been substantiated. Conclusions. Thus, the optimized tactics of complex treatment and prevention of diseases of hard tissues of the teeth prevents the progression of diseases, the development of complications, and improves the quality of life of athletes.

Recently, buccal epithelium has been used to study age-dependent processes. This approach is of particular relevance due to its non-invasiveness. The purpose of this study is to establish the normal values of the buccal cytogram in different age groups, including athletes. 200 practically healthy volunteers of different ages were examined, who were divided into 5 groups in accordance with the WHO age classification. In addition, 125 professional athletes took part in the study. All patients underwent a comprehensive dental examination and a standard cytological examination of buccal smears. It has been established that the cytological characteristics of buccal epitheliocytes, indirectly reflecting disorders of the nuclear apparatus of the cell, did not change significantly with age, but there was a certain upward trend in the number of cells with such anomalies (micronucleus, protrusions).The number of binuclear cells and the apoptotic index also slightly increase with age. At the same time, a high positive correlation was found between the apoptosis index and senile age. In young athletes, an increase in the number of buccal epitheliocytes with a perinuclear vacuole (an early sign of cell damage) was foundAnalysis of the cytological examination results of the buccal epithelium in people a slight increase in the level of cytological abnormalities in old age, in particular, signs of apoptosis. In addition, in healthy young athletes (18 years old - 44 years old), an increase in the number of cells with signs of nuclear degradation, which most likely reflects increased mechanical stress on the maxillofacial apparatus during sports activities.

The manual is intended for students of the Faculty of Dentistry, residents, practicing dentists of various specialties. Dedicated to current issues of laser dentistry. Developed taking into account world scientific and clinical practice, experimental, laboratory and clinical data obtained by the authors. This manual presents materials relating to modern ideas about the use of laser technology in dentistry, highlights modern methods of diagnosis and treatment, clinical cases are given.

Subject. Clinical and cytological manifestations of a new coronavirus infection in the oral cavity. Objectives. Identification, description and systematization of the main clinical and laboratory manifestations of a new coronavirus infection in the oral cavity in older patients. Methodology. The clinical study involved 50 elderly (60–74 years old) and senile (75–90 years old) patients who visited a dentist after an infection from September 2020 to February 2022. Study group 1 included patients with dystrophic syndrome, study group 2 – with inflammatory periodontal syndrome, study group 3 – with occlusive syndrome. Patients underwent dental and general clinical examination. The cytological study included an assessment of the cytoplasmic and karyological abnormalities level, calculating the integral indices of the buccal cytogram. Results. Most often, dental manifestations of a new coronavirus infection occur in older patients. All manifestations in the oral cavity are nonspecific, and the pathognomonic syndrome has not been established. The most common clinical manifestations are candidiasis, exacerbation of chronic periodontitis, exacerbation of herpes infection, etc. The cytological changes in the buccal epithelium reflect a general trend towards an increase in degenerative-dystrophic changes in cells, the predominance of apoptosis processes. Conclusion. Patients with dystrophic syndrome showed the greatest polymorphism of clinical manifestations associated with a new coronavirus infection (candidiasis in 59%, exacerbation of herpes infection in 47% of patients). In patients with inflammatory periodontal syndrome, exacerbation of chronic periodontitis was noted in 100% of cases. In patients with occlusive syndrome, there is an aggravation of the teeth hyperesthesia. Analysis of the integral indices of the buccal cytogram showed signs of accumulation of cytogenetic disorders after the infection.