The knowledge and actions of Brazilian schoolteachers in relation to care of acute injuries in permanent teeth were inconsistent and based on unfounded concepts, beliefs and intuition, and lack of training. Continuing education of teachers in oral care due to a dental trauma should be a good plan of action.
The control of dyslipidemia by using herbal products is an important subject for studies. In this study, we evaluated the effects of dry Passiflora incarnata L. extract over dyslipidemia, left ventricular hypertrophy, and hepatic oxidative stress of LDL receptor knockout mice (LDLr-/-). Forty 4-month old male LDLr-/-mice were distributed into four groups: Group standard diet; Group standard diet and 200 mg/kg of body weight of Passiflora incarnata L. leaf dry extract; Group high-fat diet; Group high-fat diet and 200 mg/kg of body weight of Passiflora incarnata L. leaf dry extract. After 30 days, Passiflora incarnata L. dry extract reduced the effects of the high-fat diet, with a decrease of total cholesterol, triglycerides, and increase of high-density lipoprotein (HDL), as well as a reduction of C-reactive protein, alkaline phosphatase and insulin. There was no effect on glucose, Homa index and enzymes aspartate aminotransferase and alanine aminotransferase. However, the prevention of left ventricular hypertrophy occurred, as well as lipid peroxidation and the production of carbonyl proteins, which are both oxidative stress markers. In conclusion, Passiflora incarnata L. dry extract acts in the prevention of dyslipidemia, consequently, hindering the occurrence of hepatic oxidative stress and the development of left ventricular hypertrophy by the increase of serum HDL, in mice that had the effects of a high-fat diet.
We evaluated the effects of grape juice (Vitis labrusca L.) on dyslipidemia, resistance to insulin, and left ventricular hypertrophy (LVH) in mice homozygous for the absence of the LDL receptor gene (LDLr-/-) under a hyperlipidemic diet. Methodology We divided 30 male mice (3 months old) into three groups (n = 10); the HL group was fed a high-fat diet, the HLU group received a high-fat diet and 2 g/kg/day of grape juice, and the HLS group was fed a high-fat diet and simvastatin (20 mg/kg/day). We assessed the blood pressure profile of the mice. We also determined the levels of C-reactive protein (CRP) and lipid profile, glycemic and insulinemic profiles, and calculated the HOMA-IR. Cardiomyocyte hypertrophy, interstitial collagen deposit, and the expression of CD40 ligand (CD40L) and metalloproteinases 2 and 9 were assessed immunohistologically. Results After 60 days, the mice treated with grape juice showed similar results as those of the group treated with simvastatin. The use of grape fruit attenuated dyslipidemia and insulin resistance and significantly increased the levels of high cholesterol density lipoproteins (HDLc). The antioxidant potential of phenolic compounds associated with the increase in HDLc levels in the mice of the HLU group prevented the development of LVH and arterial hypertension since it inhibited the inflammatory response induced by the CD40 pathway and its ligand CD40L. Consequently, there was a lower expression of MMP-2 and MMP-9 and lower serum levels of CRP.
33Avaliação da resistência flexural de próteses parciais fixas confeccionadas em In Ceram Zircônia Flexural strength evaluation of fixed partial dentures made in In Ceram Zirconia RESUMO Objetivo: avaliar a resistência flexural do In Ceram Zircônia em 20 corpos de prova, simulando uma prótese parcial fixa.Metodologia: foram utilizados 20 corpos de prova em forma de barra com as seguintes dimensões: 20mm de comprimento, 1,2mm de espessura e 4mm de largura e divididas em dois grupos: Grupo A -com distância do span de 12mm; e, Grupo B -com distância do span de 18mm, simulando respectivamente um e dois pônticos. As barras foram submetidas ao teste de carregamento de 3 pontos, análise fractográfica e microscópica eletrônica de varredura.Resultados: ANOVA, fator único não encontrou diferença estatística significante nos resultados da resistência flexural entre os grupos A e B, mas o resultado das tensões e a força de ruptura demonstraram o oposto.Conclusão: o aumento da distância entre os apoios não diminuiu a resistência flexural do material. Existe uma maior concentração de tensões quando se aumenta a distância entre os apoios, podendo representar uma tendência a ruptura para próteses com maior extensão. Palavras-chave: Cerâmica; Resistência de Materiais; Prótese Parcial Fixa.ABSTRACT Aim: this study evaluated the flexural strength of In Ceram Zirconia in 20 specimens, simulating a fixed partial denture.Methodology: a total of 20 specimens in the form of bar with the following dimensions: 20mm long, 1.2 mm thick and 4mm wide and divided into two groups: Group A with span distance of 12mm and Group B with span distance of 18mm, simulating one and two pontics respectively. Samples were submitted in loading test with three points, fractographic analysis and scanning electron microscopy.Results: ANOVA, single factor did not found significant statistically difference in the results of flexural strength between groups A and B, but the result of stress and rupture strength showed the opposite.Conclusion: increasing the distance between the supports did not reduce the flexural strength of the material. There is a higher stress concentration when the distance between the supports increases, this represent a tendency to break for prostheses with greater length.
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