Introduction: First trimester bleed is common symptom of pregnancy, complicating 16-25% of all pregnancies. Nearly 50% of pregnancies land up in abortions and the rest land up with poor maternal and fetal outcomes. Aims and Objectives: To evaluate whether threatened abortion makes pregnancy high risk and has effect on maternal and neonatal outcome. Materials and Methods: It is a prospective study done at hospitals attached to BMCRI during August 2015-August 2017. A total of 300 patients were included in the study, of these, 150 patients had threatened abortion (Group A) and 150 patients were as control group (Group B) without vaginal bleed. 2 groups were compared with Data regarding age, parity, symptoms, obstetric history, examination, co morbidities, pregnancy period, live birth or pregnancy loss, preterm, birth weight and APGAR, investigation findings, associated pathology and treatment modality. They were tabulated and analysed. Results: Incidence of preterm delivery, abortions, low fetal weight, and PROM was increased in threatened abortion group. Mean pregnancy period was in threatened miscarriage group was 243 days; in control group was 263 days. There was adverse influence of maternal age and abortion history on outcomes in pregnancies with threatened miscarriage. However sex of the fetuses and Apgar values after 1 and 5 minutes were similar between two groups. Conclusion: Threatened miscarriage is an important situation to predict both the maternal and fetal outcomes in late pregnancy. Maternal obstetric history on previous pregnancies should be questioned. It is therefore essential to consider these pregnancies as high risk group and provide careful antenatal care.

Introduction: Despite considerable research, the pathophysiology of preeclampsia remains unclear. However, oxidative stress has been attributed to be the causative factor of preeclampsia. Uric acid is a marker of oxidative stress, tissue injury and renal dysfunction. Aims and objectives: To study the association of raise in serum uric acid level in severe preeclampsia and to evaluate perinatal outcome in severe preeclampsia with raised serum uric acid. Methodology: This is a prospective clinical observational study undertaken to study the significance of estimating serum uric acid in severe preeclampsia and perinatal outcome in severe preeclampsia and compare it with normotensive pregnant women. This study was conducted for a period of one year from October 2018 to September 2019 in the department of obstetrics and gynaecology, Vanivilas hospital, Bangalore. Results: Mean serum uric acid in study group is 7.16mg/dl & in control is 3.52mg/dl. The difference in mean serum uric acid concentration between study and control group was found to be statistically significant (p<0.05). The highest mean serum uric acid concentration is in preterm study group (8.23mg/dl) followed by term study group (7.52mg/dl). The difference between them is statistically significant (p<0.05) In the study group the MSUA concentration is found higher in LBW & VLBW babies compared to normal birth weight babies & the difference in MSUA concentration was statistically significant in study group (p<0.05).

Introduction:In placenta previa, placenta is situated partly or wholly in lower segment. Bleeding occurs from the placental site when the lower segment stretches, which can be fatal to both the mother and the foetus. Aims and Objectives:To study the relation between type of placenta previa and mode of delivery and to study the neonatal and maternal out come in cases of placenta previa. Methodology: Prospective Observational study was done in the department of obstetrics and gynaecology, Vanivilas hospital, Bangalore from September 2018 to August 2019. Results were analysed and concluded. Results: This study consists of 114 cases complicated with placenta praevia.19 cases (16.67%) had previous history of abortion, 13 cases (11.40%) had previous history of caesarean section and 2 cases (1.75%) had previous history of placenta previa. There were 51cases (44.74%) of minor degree of placenta previa and 63 cases (45.16%) of major degree of placenta previa. Conclusion:Good ANC at the level of primary health centre, availability of a specialized professional at the level of PHC, for early recognition and diagnosis of placenta previa, correction of anemia during antenatal period, good counselling and reference to a tertiary hospital at an early stage will probably help in decreasing the maternal morbidity and perinatal mortality.