Treatment effect was much lower after <8 weeks of treatment compared with that after 12 weeks (the comparison of these groups was not available because the initial samples were not). To the 24th week, 63.9% of the patients responded to treatment, 43.4% achieved remission. Partial response and stable positive dynamics to the 12th week (about ½ of the patients achieved remission) were predictors of response with treatment duration <24 weeks. Based on the results obtained, the authors developed algorithms for choosing treatment tactics in patients with late onset depression in dependence of the results of the first 12 weeks of psychopharmacotherapy.

The market of products from natural fur and skin takes a special place in the Russian market of clothes, first of all it is connected with that fact that this production is one of the most expensive of all type of goods of light industry, and also in connection with severe climatic conditions of the Russian Federation demand for products from natural fur and skin is high during an autumn and winter season. In article an attempt to analyse competitive strategy of players of the market pushno – the fur industry is made. Conclusions became results of research that for the companies of the fur and fur industry a key role play: 1) The known brand which causes positive associations in the client and installs confidence in the quality, offered production; 2) The wide model range offered on a choice of the client; 3) The qualified personnel which not only adjusts the consumer on purchase, but also can answer all questions concerning quality of production, the cut, actual trends, ruled socks, cleanings, storages, etc.; 4) Planning and registration of trade space (window dressing and effective zoning of space of shop).

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Today practice of creation own online of business is widespread in the USA and Europe while in Russia similar practice only gathers gradually a turn. Nevertheless, in Russia start treating a similar kind of activity more seriously. An objective of this research - to determine expediency of maintaining by the luxury fashionable companies of commercial activity online on the example of the largest foreign players. As a result of research it is defined that purchase online of goods of haute couture – a question ambiguous as many do not find in general need for acquisition of similar things owing to economic prerequisites and personal claims. During research it was revealed that the beginning of active sales of luxury goods, in particular clothes subjects, can negatively influence brand representation for perception of the consumer. The following conclusion concerns the main channel of communications between the buyer and the seller. Despite probable negative effects of sales online, nevertheless, the companies should be reoriented and conduct vigorous marketing activity in a network. Physical shops – an important aspect of maintenance of the status, but it is possible to assume that this services industry is developed quite strongly. Other situation is about online marketiny for фэшн the industries, after all in fact, 10 years ago the companies as Chanel, Dior were categorically against similar shift of values towards digital technologies, today it is inevitable.

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