The characteristic morphology of a not intentionally stimulated hyalocyte is described, using TEM and perfusion fixation. The best results were obtained by retrograde perfusion via the abdominal aorta with a glutaraldehyde- and formaldehyde-containing fixative. The cells, situated in the cortical area of the vitreous body, show mostly an indented nucleus, primary and secondary lysosomes, mitochondria, cisterna, clusters of free ribosomes and a Golgi apparatus. Bristle-coated micropinocytotic vesicles can also be distinguished and in some cells a centriole is visible. Sometimes the cells show many cytoplasmic protuberances. Morphologically the majority of those cells can be considered as resting macrophages.

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Experimental lymph stasis demonstrates the hepatic lymph vessel system by unfolding of the branching lymphatics. The lymphatics are limited to the interlobular connective tissue. The lymphatic wall consists of a flat endothelium without pores and without a continuous basal membrane. The endothelial cells show overlapping processes and are suspended in a net of delicate filaments. Lymph and bile stasis produce separation of the endothelial junctions. Only reversible changes of liver parenchyma are seen after pure lymphostasis. The storage of tantalum powder by the liver is reduced by the Imphostatic edema. The significance of lymph stasis resides primarily in its existence as an additional stressor. Simultaneous lymph and bile stasis definitely speeded up the cirrhotic process. The experimental models should lead to a greater emphasis of the importance of the hepatic lymphatic drainage system, and especially of lymphostasis as an important additional factor in pathogenesis of human diseases.

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