Cervical cancer is one of the most preventable and treatable malignancies, however, it still has high incidence and mortality rates, especially in less developed countries. For Brazil, the estimate is more than 16,000 new cases and more than 6000 deaths annually. Despite this, vaccines against HPV (responsible for cervical cancer) are effective and promote a significant decrease in infections and neoplastic lesions of the cervix.
Introdução: A obesidade consiste em uma doença crônica resultante do comprometimento metabólico funcional do organismo, cuja consequência principal são as doenças cardiovasculares secundárias, apresentando, então, como fator de risco o sobrepeso em adultos. Diante disso, tornou-se imprescindível a busca de uma abordagem farmacológica em auxílio às mudanças de hábitos alimentares e de rotina de atividades físicas, a fim de minimizar as chances de desenvolvimento e recidiva da enfermidade. Objetivo: avaliar o potencial medicamentoso da semaglutida como terapia adjuvante para o emagrecimento em adultos que demonstram valores de índice de massa corporal acima de 25. Metodologia: trata-se de uma Revisão de Escopo, elaborada de setembro a outubro de 2022, mediante pesquisa na base de dados MEDLINE mediante os Mesh Terms utilizados na busca pela plataforma PubMed. Para a revisão, selecionou-se 20 artigos, os quais obedeceram aos critérios de elegibilidade. Resultados: os achados principais evidenciaram os benefícios do medicamento para perda de peso sustentada em pacientes obesos, redução de risco cardiometabólico e melhora do controle glicêmico. Além de efeitos natriuréticos e diuréticos, que promovem diminuição da pressão arterial e melhora em processos inflamatórios. Conclusão: embora não haja consenso definitivo na comunidade científica sobre os possíveis efeitos associados ao uso da semaglutida, as literaturas confluem na mesma direção no que concerne à consolidação da semaglutida como uma droga promissora no processo de emagrecimento de adultos com sobrepeso e obesidade.
Endometriosis is a clinical and recurrent condition characterized by the presence of functional endometrial tissue outside the uterine cavity and myometrium. It is estimated that 6% to 10% of women of reproductive age, 50% to 60% of adolescents and adults with pelvic pain, and up to 50% of women with infertility are pregnant from the condition. However, this proportion tends to be even greater due to the difficulty in diagnosing it: because it presents different symptoms, lack of information from health professionals, and a high-cost diagnostic test. Another aggravating factor is the average time from the onset of symptoms to the medical diagnosis, which even today ranges from five to ten years; this delay has consequences for disease progression, as it prevents early treatment, which is important for improving pain levels and physical and psychological well-being. Aware of these mishaps, it is therefore important to assess the difficulties faced by doctors in the diagnosis of endometriosis in the public health system, in Brazil, the Unified Health System (SUS). With this purpose, a cross sectional was carried out, developed in the virtual environment using traffic in Google forms, with the difficulties quantified in the Likert scale. Participating physicians pointed out a medium difficulty for patients with endometriosis to access the consultation (58%) and moderate difficulty (52%) to perform an ultrasound examination; also signaled great difficulty in performing magnetic resonance imaging (77%) and laparotomy (61%) in these patients.
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