Rice starch (RS) and carboxymethyl cellulose (CMC) are natural polymers that can be widely used for numerous biomedical applications such as hydrogels, capsules, drug delivery system, wound dressing. The purpose of this study was to prepare and investigate the appropriate weight ratio of RS/CMC blend films by solution casting technique. The swelling ratio and solubility were evaluated. The mechanical properties, intermolecular interaction, and morphology were also analyzed by the universal mechanical testing, Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM), respectively. The results indicated that the suitable ratio of RS/CMC blend film was 60/40. The swelling ratio, solubility, tensile strength, and elongation at break were 46.8±0.3 times, 21.63±0.72 %, 30.4±1.5 MPa and 5.76±0.31 %, respectively. Moreover, the physical linkages exhibited mainly between the hydroxyl groups of RS and the carboxyl groups of CMC. In addition, the cross-sectional SEM images of blended films showed the miscibility of RS and CMC. This study suggested that the RS/CMC blended film can be used as a hemostatic film.

Rice-based gel is intended to be a coupling agent for usage in ultrasonic application, which made from blending of rice starch powder, sodium hydroxide, carboxymethyl cellulose, glycerin, and water. In this study we test the products for safety and efficacy in 100 patients, by four physicians. The imaging results revealed that, when compared with standard ultrasound gel, rice gel can produce equal clearness but with better echogenicity. So, rice-based ultrasound gel should be an alternative choice for general hospitals.

Biodegradable scaffold is an accepted and commercialized medical alternative choice for bone regeneration. In this project, we used our new invention, porous starch-Hydroxyapatite (HA) composite for in vivo clinical trial. The products were prepared from medical grade Thai rice starch mixed with high purity (>97%) HA powder from fresh cow bone, and already passed in vivo animal biocompatibility test, then processed by freeze-drying. There were 44 volunteers from orthopedic and neurosurgical division, 4 and 40 patients, respectively. The results were assessed by operative surgeons and nurses, pre-and intraoperative period, including size appropriateness, comfort handle, ease of cutting, void space filling, water stability, product weight, shelf storage, package opening, contamination risk and waste removal. All average satisfactory scales were more than 95% rating. For postoperative period, at least 6 months, the soft tissue swellings around surgical areas were resoluted about 3 days as usual healing process. There were no any symptoms or signs of infection or allergic reactions. The follow up of x-ray imaging showed well ossification about 2 months. All patients have gained good functional performance. So porous starch-HA composites biomaterial can be used for human bone and skull regeneration with completely safety and efficacy.

To study the effect of addition purified cow bone (CB) powder (20, 30, 40 and 50 wt%) in slurry suspension of retrograded rice starch (RRS). The composite sponges were used as in bone repair. The RRS-CB composite sponges were prepared from the mixture of RRS, CB and additive into distill water. The prepared samples were characterized including SEM, XRD, physical and mechanical properties. The results of optimized condition have shown the samples of 40 wt% CB that had the swelling rate as 102± 0.01%, area of expansion was 20 ± 0.03 % for 72 hours and the compressive strength was 64.35±0.05KPa. In addition, it was found that this content resulted in sufficient soft porous material, foldable by hand and self recovered body.

The purpose of this work was to evaluate the efficiency of oil sorption of silica particles modified by three different types of cationic polymers and a cationic surfactant. Low-molecular-weight polyethyleneimine (LPEI), high-molecular-weight polyethyleneimine (HPEI), polydiallyldimethylammonium chloride (PDM), and cetyltrimethylammonium bromide (CTAB) were used to modify the silica particles and then compared their performances for oil removal. The scanning electron microscope and zeta potential measurements were used to analyze the surface characteristics of unmodified and modified silica particles. Adsorptions of motor oil and palm oil on the modified silica particles have been investigated under various parameters such as the silica particle size, the oil concentration, the polymer/surfactant concentrations, and the pH. The results have shown that the modified silica particles enhanced the oil sorption ability by approximately 10–20 times depending on the size of silica particles, pH, and the type of polymer/surfactant used when compared with the unmodified silica particles. The highest palm oil adsorption values of LPEI-silica, HPEI-silica, PDM-silica, CTAB-silica, and unmodified silica were 2.40, 2.10, 1.95, 1.50, and 0.15 g/gsilica, respectively. Moreover, the oil sorption of the modified silica particles was increased by approximately 30–50% for the smallest-sized silica particles.