To evaluate the fruit of Pyrus communis L. for its wound healing property by different wound models using wistar albino rats. The wound healing activity of ethyl acetateandethanol extracts of fruits of Pyrus communis (EAEPC and EEPC 200 mg/kg) was investigated by various wound healing model in normal rats such as excision, incision and dead space wound model. Povidone iodine is used as standard. The wound was created according to standard procedure in different model and the wound contraction area, epithelization period, scar area, breaking strength and weight of granulomawere assessed. The phytochemical screening and total phenolic content was estimated in both extracts. Hydroxyproline content of harvested granulation tissue was estimated in all groups of animals. The result suggests various extracts of Pyrus communis have significant (p < 0.01) wound healing activity in different models. In this study we concluded that fruit of Pyrus communis is natural remedy for treating different type of wounds.

Introduction: To identify the various phytoconstituents present in the plant Sphaeranthus indicus by using gas chromatography and mass spectrometry. Meth­ods: The fruits of Sphaeranthus indicus were extracted with Different solvents of increasing polarity. The methanol and ethylacetate extract were subjected to GCMS analysis to detect the phytoconstituents. Results: Totally 26 compounds were identified. Among these 13 constituents in methanol extract and 13 constituents in ethylacetate extract were identified during the GC-MS analysis. Stigmasterol and lupeol which were identified in the plant is considered to have antiarthritic properties. Keywords: Sphaeranthus indicus, Gas chromatography, Mass spectrometry.

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