Objective: To study the effect of maternal age on incidence of placenta previa. Introduction: Placenta previa is a serious and life threatening obstetric complication where the placenta lies within the lower segment of the uterus, presenting an obstruction to the cervix and to delivery. A trend of increasing placenta previa incidence was observed in the past decade mainly because of an increasing caesarean section rate and advancing maternal age at the time of pregnancy. Methods: This study was a prospective study conducted in a teaching medical college and hospital over a period of three years [2011][2012][2013][2014]. A detailed history was taken according to our proforma for all pregnant women at or after 32 weeks who attended the hospital in the study period. As per inclusion and exclusion criteria of our study, the study population was selected. All other risk factors for placenta previa except maternal age were excluded. The association between maternal age and placenta previa was analysed. Placenta was located by Transabdominal ultrasound and patients with placenta previa were followed up regularly. Results: Our study showed that women aged ≥35 years or more had increased risk of placenta previa(3.6%) which was statistically significant (p<0.05) by Chi-square test. Conclusion-Advancing maternal age (≥ 35years) appears to increase the risk of placenta previa independent of other risk factors.

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Introduction: Spinal anaesthesia is the preferred method of anaesthesia for elective lower segment caesarean section (LSCS). It has a shorter onset time, but is associated with hypotension and bradycardia,which at times may be deleterious to both mother and fetus. Aim of Study: To evaluate the effects of intravenous administration of ondansetron prior to spinal anaesthesia on the hemodynamic responses in the mother specifically hypotension and bradycardia. Materials and Methods: The study was a hospital based prospective, double-blinded, randomized, placebo controlled study in our teaching medical college and hospital over a period of 6 months-February to July 2015. As per inclusion and exclusion criteria of our study, study population (72 patients) was identified who were planned for elective LSCS. They were randomly allocated into two groups. 5 minutes prior to spinal anaesthesia, group O (n =36) received 4mg IV Ondansetron and group P (n = 36) received physiological saline. Blood pressure and heart rate were monitored once in 5 minutes for 30 minutes, and requirement of vasopressors was noted. Results: Hypotension was significantly lower in group O when compared to group P. Bradycardia was less in number in group O but it was statistically insignificant. Vasopressor requirement was also lower in group O patients.Conclusion: Intravenous Ondansetron 4mg given 5 minutes prior to spinal anaesthesia significantly reduces the hypotension. The episodes of bradycardia as well as the requirement of vasopressors in parturients were low in ondansetron group, which was found to be statistically insignificant, may be due to less number of study population.

Introduction: Pregnancy in chronically undernourished women with low maternal weight results in delivery of low birth weight babies. Aim of the Study: our aim was to study the correlation between maternal weight during pregnancy with fetal outcome measured in terms of fetal weight and perinatal mortality. Materials and Methods: This was a hospital based prospective study conducted in the department of obstetrics and gynecology in our teaching medical college and hospital over a period of 2 years extending from Jan 2011-Dec 2012. All the cases delivering in this hospital were taken for this study. Total of about 1449 cases were taken for this study. Results: In this study the average weight of patients was found to be 51.88±7.64 kg. The mean birth weight was found to increase with increasing maternal weight. The difference in the mean birth weight was found to be statistically significant between the different groups (P<0.01) except between those patients with weight in range of 50-60 and those above 61 kg (P>0.05).There was found to be a statistically significant increase in birth weight with increase in maternal third trimester weight from less than 45 kg to 55 kg. Differences in perinatal mortality between these groups were found to be statistically insignificant (P>0.05). Conclusion: There was statistically significant increase in mean birth weight with increase in maternal weight upto 60 kg. There was no correlation between perinatal mortality rate and maternal weight.