This paper reports the effect of the various ceramic coatings viz., hydroxyapatite (HA) and partially stabilized zirconia (PSZ) on the bond strength between the bone and implant, and cell compatibility of screw-shaped Ti-6Al-7Nb dental implants. Electrophoretic deposition technique (EPD) was used to obtain a uniform coating of one of the three types of ceramic layers (HA, PSZ and 50%HA + 50%PSZ) on the screws. Structural investigations were carried out on the prepared HA powder and the modified surfaces of the Ti-6Al-7Nb alloy using different techniques, namely X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR). The in vivo studies were performed by the implantation of screw-shaped uncoated and coated implants in the tibia of white New Zealand rabbits. To understand the bone-implant interface, biomechanical test was carried out after 2, 6 and 18 weeks healing periods. There was increased mechanical strength (torque value) of bone-implant interface with time, and the highest increment in the bond strength was recorded for implants coated with a 50% HA and 50% PSZ. Histological results show that the coated Ti-6Al-7Nb screws after 18 weeks of the implantation seem to be well-tolerated by the bone since no adverse tissue reaction was evident. However, there was a faster reaction of bone towards the coated implants compared to the uncoated one. The histochemical stain studies shows higher cellular activity and mature bone formation on all the samples.
Background: Periodontium mainly exposed to injury by trauma or pathologic diseases, Aloe vera is a plant has many basic ingredients in its extracted gel that acts as wound healing accelerator in addition to that it's safe, and economical and without recordable of side effect. This study aimed is to evaluate the effect of topical application of Aloe vera on expression of syndecan-1 by periodontium tissue. Materials and methods: Thirty six male Albino rats were subjected for periodontium defect by electric scaler on the distal sides of both lower anterior teeth. The animals divided into two groups; control group (without treatment) and the experimental group treated with 1µLAloe vera gel/normal saline. Periodontal healing was examined at periods (3, 7, 14 days) for immunohistochemical localization of syndecan 1. Results: Immunohistochemical examination of this study revealed that the aloe vera treatment increase expression of syndecan 1 by epithelial cell, osteoblasts, fibroblast, stromal cells and with highly significant differences in comparison with control and saline. Conclusion: Aloe vera gel may affect the expression of syndecan 1 which seems to play a role in periodontium healing.
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