Renal primitive neuroectodermal tumor (PNET) is a rare entity. It should be differentiated from other primary renal malignancies. The differentiation of the malignant small round cell tumors may be challenging; however, it is essential for better management of the patient. We report a 45-year-old male having complaints of pain in the abdomen, hematuria, and mass in the abdomen for 6 months. Abdominal and pelvic sonography finding showed cystic-solid, right renal mass suggestive of malignancy. On histopathology diagnosed as malignant small round blue cell tumor suggestive of primitive neuroectodermal tumor. On immunohistochemistry, CD99 positivity confirmed the diagnosis of primary PNET of the kidney. We are presenting this case for its rarity, clinical presentation, and pathological findings.
Coronavirus disease 2019 (COVID-19) is an infection caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). COVID-19 infection may be associated with a wide range of bacterial and fungal co-infections. Herewith a case of 46 year-old male patient of post COVID-19 developed co-infection. He had received steroid treatment and improved in last month. He is known case of diabetes type II since last one year and was on treatment. Now presented to our hospital having fever, facial pain, and swelling mid-face region. His RT-PCR test was positive. The CT scan of the nasal septum, medial walls of bilateral maxillary, ethmoid, sphenoid and frontal sinuses exteding into bilateral nasal cavities. Features suggestive of infective pathology invasive fungal rhinosinusitis On clinical, radio imaging and on histopathological findings diagnosed as maxillary mucormycosis with actinomycosis. Conclusion: We are presenting this rare case of COVID-19 associated with co-infection of mucormycosis and actinomycosis for its clinical, radio imaging, and on histopathological findings. Key words: Coronavirus Disease 2019 (COVID-19), Mucormycosis, Actinomycosis, Co-infections.
Study of Coagulation profile in preeclampsia and eclampsia comprised of 258 cases which were categorized as preeclampsia, eclampsia and control group with 86 cases in each group. A total number of 258 patients were studied which were categorized as the control group, preeclampsia group and eclampsia group with 86 cases in each. Preeclampsia was further classified as mild preeclampsia (48/86) and severe preeclampsia (38/86). Among all patients, thrombocytopenia was found in 61% of patients. All patients in the control group had platelet counts within the normal range. The method used in the present study is an analytical case-control study, carried out in the Department of Pathology in our institute. Our study includes cases of preeclampsia and eclampsia coming to the Department of Obstetrics and Gynaecology during the period of two years from May 2015 to April 2017. Newly diagnosed Preeclampsia and eclampsia patients in the third trimester of age 18 to 30 years. From this study, it can be concluded that coagulation profile can help to assess the severity of preeclampsia and eclampsia and thus can help to reduce complications if treated early. Thus as inconclusive of this study of coagulation profile has significant value and impact on management and outcome of cases of preeclampsia and eclampsia.
The present study was a two year prospective study of FNAC of total 158 palpable thyroid lesions, reported according to The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC). Out of 158 cases, 36 patients underwent surgical excision and cyto- histopathological correlation was done in these cases. Majority of the patients were females, with a ratio of female to male as 8.9:1. The duration of the palpable thyroid swelling in the present study ranged from less than 1 month period to more than 5 years. Size of thyroid swelling varied from as small as 1 cm to as large as 18 cm in diameter. The procedure was done by both aspiration and non-aspiration techniques and any significant difference in terms of the yield of material by either of the method, was not observed in the present study. TBSRTC is an excellent reporting system, as it showed specificity of 100 % in the present study, which helped to diagnose benign cases correctly and to avoid unnecessary surgery.
In this study, there are possible causes of two years from June 2015 to May of 2017. During study includes 130 cases of cholecystectomy specimens from January 2013 to June 2017. The objective/purpose of the study is to correlate histopathological findings with various biochemical parameters viz. fasting blood sugar level, lipid profile, etc. Amongst the four cases of adenocarcinoma, 3 (75 %) cases showed serosal infiltration and liver infiltration. Out of a total of 130 cases, 69 (53%) were female, and 61 (47%) were male. Out of 4 patients of adenocarcinoma 2 (50%) patients expired during the postoperative period, while 2 (50%) patients improved. Diabetic patients constitute 13.84% of total cholecystectomy patients, so diabetes proved to be a risk factor for the development of gallbladder diseases with statistically significant Odds Ratio (2.66). Results from this study show that a variety of gallbladder lesions are observed in cholecystectomy specimens. The most common lesion observed was chronic cholecystitis with cholelithiasis 99 cases (76.1%), followed by acute cholecystitis 12 cases (9.2%). The present study was undertaken to emphasize the role of histopathological examination in cholecystectomy specimens and its correlation with clinical presentation. Histopathological examination many time reveals an unusual diagnosis bearing significant implications on the treatment, prognosis and outcome of the patient. Hence, the study was undertaken to emphasize the role of histopathological examination in cholecystectomy specimens and its correlation with clinical presentation.
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