In this prospective study, we investigated the impact of SARS‐CoV‐2 infection on semen parameters in a cohort of men who had recently recovered from COVID‐19. A total of 24 men who had recently recovered from mild COVID‐19 were included in the study. Their semen parameters were normal before COVID‐19 according to the World Health Organization 2010 reference values. Semen samples were collected from these participants in the recovery phases of COVID‐19. To determine the effect of SARS‐CoV‐2 infection on semen parameters, the patients' pre‐COVID‐19 and post‐COVID‐19 semen analyses were compared. The mean age of the participants was 34.7 ± 6.4 years. The median interval between the positive nasopharyngeal swab test and obtaining semen samples was 111.5 (158) days. There was no significant difference in semen parameters before and after COVID‐19 in terms of semen volume ( p = .56), sperm concentration ( p = .06), and progressive motility ( p = .14). Total motility ( p = .01) and total motile sperm count ( p = .02) decreased significantly after SARS‐CoV‐2 infection compared to the pre‐infection values. This study demonstrated that sperm motility and total motile sperm count were the semen parameters which showed a significant reduction in cases with a history of mild COVID‐19.
In this study, it was aimed to determine the effectiveness of transabdominal ultrasonographic imaging on the 35th day of pregnancy in determining the pregnancy status and number of fetuses in sheep. 69 Awassi sheep were used in the study. Sheep were mated after oestrus synchronization during the breeding season. On the 35th and 50th days after mating, a pregnancy examination was performed twice transabdominally in each animal by ultrasonography. Sheep with single/multiple offspring were noted according to examination performing on day 35 and lambing record. According to ultrasonography results, early foetal death rate was determined as 6.1%. Sensitivity, specificity, positive predictive value, negative predictive value ratios for pregnancy examination findings and single/multiple offspring data by transabdominal ultrasonography on day 35 were determined as 91.30%, 100%, 100%, 83.3% and 38.46%, 81.25%, 76.92%, 44.82%, respectively. While the consistency of transabdominal ultrasonographic imaging for pregnancy on day 35 and 50 were high agreement (Kappa=0.864, p<0,001), consistency of single/multiple pregnancy findings on day 35 and at birth were low (Kappa=0,170, p>0.05). The rates of transabdominal ultrasonographic examination on day 35 for correct diagnosis of pregnancy status and the number of fetuses were found as 93.93% and 54.76%, respectively. Finally, it can be concluded that transabdominal ultrasonographic examination on day 35 for early pregnancy diagnose in sheep is highly effective in determination of pregnant sheep, and recurrent examination on days 35 and 50 may be useful for detecting of early foetal deaths. In order to determine the number of fetuses, repeated examinations should be performed in the following days of pregnancy.
Öz: Bu olguda kısırlaştırılmış bir köpekte vajinal leyomiyosarkomun tanımlanması amaçlanmıştır. Olgunun materyalini vulvasından sarkan bir kitle şikayeti ile kliniğimize getirilen melez erişkin dişi bir köpek oluşturdu. Köpeğin anamnez bilgilerinde daha önce kısırlaştırılmış olduğu ve son iki aydır vulvasından sarkan bir kitlenin olduğu öğrenildi. Fiziksel muayenede köpeğin genel durumunun iyi olduğu belirlendi. Vajinal muayenede; vulvadan dışarı sarkan, saplı, pembemsi renkli sert bir kitle tespit edildi. Kitlenin köpeğin vajinasının dorsal duvarından köken aldığı belirlendi. Kitleye tümöral bir yapı tanısı konularak operasyonla uzaklaştırılmasına karar verildi. Makroskobik olarak 5.6x3.2x1.7 cm boyutlarında, 43 gr ağırlığında, pembemsi beyaz renkte, elastik kıvamlı kitle gözlendi. Mikroskobik olarak hiperkromatik çekirdekli, birbirine çaprazlar yapan, anaplastik şekilli, iğsi ve yuvarlak şekilli hücreler arasında çok çekirdekli dev hücreleri, nekroz alanları ve yer yer mitozlar dikkati çekti. Makroskobik ve mikroskobik özelliklerine göre tümöre leyomiyosarkom tanısı kondu. Sonuç olarak; vajinal leyomiyosarkomun köpeklerde nadir görülmesi ve köpeğin kısırlaştırılmış olması nedeniyle olgunun makroskobik ve histopatolojik bulgularının literatür verilere katkı sağlayabileceği düşünüldü.Abstract: In this case report it was aimed to determine vaginal leiomyosarcoma in a neutered bitch. The material of this case was an adult mixed breed neutered bitch brought to our clinic complaint with a mass hanging from the vulva. In the history, it was learnt that bitch had been neutered before, and there had been a mass hanging from the vulva since last two months. The condition of the bitch was determined to be good in the physical examination. In the vaginal examination, stalked, pinkish a hard mass hanging from the vulva was detected. It was determined that the mass was originated from dorsal vaginal wall of the bitch. It was decided to remove with operation by diagnosing as a tumoral structure. Macroscopically 5.6x3.2x1.7 cm in diameter, 43 gr in weight, pinky-white in colour, elastic in consistence mass was observed. Microscopically hyperchoromatic nucleus, crossed each other, anaplastic, round-shaped spindle cells include multinucleated giant cells, necrosis and mitotic figures were noted in places. According to macroscopic and microscopic features, the tumor was diagnosed as leiomyosarcoma. Consequently, because both the vaginal leiomyosarcoma rarely seen in the dog and occurenced in sterilized dog, macroscopic and histopathologic findings of the case were considered to be able to contribute to the literature.
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