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Oral pulse granuloma is one of the terms used to describe oral inflammatory lesions characterized microscopically by the presence of giant cells and hyaline rings. The various names proposed for these lesions reflect the lack of agreement regarding their pathogenesis. One theory advanced claims that the process represents a foreign‐body granulomatous reaction to implanted vegetable particles, more specifically those of pulses/legumes. In this study an animal model was developed where homogenized cooked legumes were implanted into the orofacial region of rats. Animals were killed at varying intervals ranging from one day to six months and the tissues associated with the implanted material were removed and processed for light microscopy. The experimentally produced lesions had many features similar to those found in humans, the similarities becoming more pronounced with time. The results indicate that the cellulose moiety of food particles of plant origin accidentally implanted into human tissues may cause the granulomatous reaction known as oral pulse granuloma.

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Chau MNY, Radden BG. Intra-oral salivary gland neoplastns: a retrospective study of 98 cases. .1 Oral Pathol 1986: \5: 339-342.The findings of a retrospeetive study of 98 tninor salivary tieoplasms are reported. The patients' ages ratiged from 13-79 years and there was an equal sex distribution. Sixty-one of the lesions were benign. 53 being pleomorphic adenotnas and 8 nionomorphic adenotnas. Of the tnalignant tumors. 19 were muco-epiderrnoid tumors. 12 adenoid eystie eareinomas. 4 adenoeareinornas, 1 careinoma ex-pleornorphic adenoma and 1 epiderrnoid earcinoma. One striking finding was the difference in age at the time of presentation for patients with muco-epiderrnoid tumors eompared with those with adenoid eystie eareinomas. Seventy-four pereent of the patients with muco-epiderrnoid tumors were under 50 years of age, but 75% of those with adenoid eystie ear'einornas wer'e over 5t) years.

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