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IntroductionIn obstructive sleep apnea ( OSA), there is increased oxidative stress. Aim of this workThis study aimed to examine the effect of continuous positive airway pressure (CPAP) on oxidative stress occurring in OSA. Participants and methodsThe present study was carried out on 40 individuals classifi ed into four groups: group I included 10 control participants, group II included 10 obese individuals without OSA, group III included 10 patients with mild to moderate OSA, and group IV included 10 patients with severe OSA. Sleep study was carried out, and Thiobarbituric acid-reactive substance and superoxide dismutase enzyme were measured. ResultsThiobarbituric acid-reactive substance was signifi cantly increased, but superoxide dismutase was signifi cantly decreased in group IV, and CPAP led to an improvement in this condition. ConclusionOSA leads to increased oxidative stress that improved with the use of CPAP.

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There is a link between obesity and both, asthma and COPD. Aim of the work: To study effect of weight reduction on pulmonary function tests of obese COPD and bronchial asthma patients.Subjects and methods: 2 groups were included, group(G)I, 30 obese COPD and GII 30 obese bronchial asthma patients. Pulmonary function tests were done to all participants before and after weight reduction.Results: GI showed increased FRC, ERV and RV significantly, IC was significantly decreased and GII showed increased FEV 1 , FVC, FEV 1 /FVC, PEFR, FEF 25-75% and ERV significantly after weight reduction.Conclusion: Weight reduction improved airway obstruction, increased ERV, RV, FRC and DLCO either significant or insignificant in asthma and COPD.

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