Avocado (Persea americana) contains a lot of vitamin A, vitamin B, vitamin C and vitamin E which is good to be used in skin care. One of the cosmetics for skincare is lotion, which is a liquid emulsion consisting of oil phase and water phase stabilized by emulgator. Lotion is used to protect and maintain skin moisture level. The purpose of this research was to formulate and evaluate the lotion in order to assure the physical characteristic and stability were accepted according to the Handbook of Pharmaceutical Excipients and Indonesia Pharmacopeia requirements.Formulation were made by using these following ingredients: glyceryl monostearate, cera alba, tween 80, glycerin, liquid paraffin, benzyl alcohol, perfume, aquadest. The study used 2 variation of concentration, which is 0.5% and 1% avocado extract as active substance, besides there is variations in glyceryl monostearate (5.5% and 5.7%), cera alba (2.7% and 2.9%), tween 80 (3.5% and 3.7%), glycerin (10% and 12%), liquid paraffin (10% and 12%), and benzyl alcohol (0.15% and 0.17%) in formulations I and II. Lotion was then tested for its physical properties, which include organoleptic test, homogeneity test, pH test, and spreadability test, lastly hedonic and irritation test were also being examined.Based on the results of physical properties test, both lotion formulations showed a viscous texture, beige and dark beige color with a distinctive odor, homogeneous, not irritating, have a pH value in the range of 4. 55-5.31 with 4.9-5.15 cm spread. In the hedonic test on 10 panelists, lotion I formulation gave the most satisfaction score and comforty from respondents. Respondent's satisfaction on the appearance comprise the texture, color, and odor. Besides, viscosity and spreadability were also marked as how comfort the lotion is when it was applied to the respondent's skin.

Penggunaan body scrub merupakan salah satu perawatan kulit untuk mengangkat sel- sel kulit mati akibat radikal bebas, labu kuning merupakan salah satu tanaman yang banyak mengandung beta karoten serta vitamin C dan E yang berfungsi sebagai antioksidan alami untuk menangkal radikal bebas pada kulit. Penelitian ini bertujuan untuk membuat formulasi sediaan krim body scrub yang mengandung sari labu kuning (Cucurbita moschata). Sari labu kuning diformulasikan dalam variasi konsentrasi 10%, 15% dan 20%. Evaluasi formula krim body scrub yang dilakukan meliputi uji homogenitas, organoleptis, pH, stabilitas menggunakan metode cycling test, uji iritasi pada kulit, dan efektivitas pada kulit dengan mengamati kemampuan menghaluskan kulit dan meningkatkan kadar air pada kulit dengan menggunakan perangkat skin analyzer. Hasil penelitian menunjukkan bahwa sediaan krim body scrub sari labu kuning (Cucurbita moschata) homogen saat difomulasikan, memiliki bentuk, warna, tidak berubah setelah pengujian stabilitas dengan metode cycling test, dan mempunyai nilai pH yang memenuhi persyaratan pH kulit, serta tidak menimbulkan iritasi pada kulit sukarelawan. Sediaan yang dengan konsentrasi sari labu kuning 20% (F3) memiliki efektivitas paling mendekati kontrol positif yaitu mampu memperbaiki kehalusan kulit (evenness) hingga 50,00% dan meningkatkan kadar air (moisture) hingga 46,33%. Kesimpulan dari penelitian ini adalah sari labu kuning (Cucurbita moschata) dapat diformulasikan dalam bentuk sediaan krim body scrub yang stabil dan mampu memperbaiki kondisi kulit yang kasar menjadi lebih baik.

Patchouli oil contains patchouli alcohol as the main component which is a tricyclic tertiary alcohol sesquiterpene compound that is insoluble in water. Microemulsion is a droplet dispersion technology that combines an insoluble liquid with another liquid. The role of surfactants in helping the dispersion process of microemulsion formulation is by reducing the interfacial tension. Microemulsion is a supersolvents carrier, so that both hydrophilic and lipophilic can be administered through a microemulsion system. The purpose of this study was to formulate patchouli oil into a stable microemulsion preparation. This research was conducted by making 4 preparations of patchouli oil microemulsion containing 5% (F1), 10% (F2), and 15% (F3) patchouli oil, and microemulsion without patchouli oil (F0). Evaluation of microemulsion preparations includes organoleptic test, pH measurement, density determination, viscosity test, freeze and thaw test, centrifugation test, and particle size analysis. The test results showed that the microemulsion containing 5% patchouli oil had the most stable characteristics compared to other formulas.

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