FORMULASI, KARAKTERISASI DAN UJI STABILITAS MIKROEMULSI MINYAK NILAM (Pogostemon cablin Benth.)

Iskandar, Benni; Lukman, Anita; Tartilla, Raesa; Surboyo, Meircurius Dwi Condro; Leny, Leny

doi:10.36387/jiis.v6i2.724

Cited by 8 publications

(9 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Preparations with the type (o/w) have the advantage that they are less sticky and easy to remove by washing and are easier to apply to the skin and leave a comfortable feeling compared to cream preparations of the water in oil (w/o) type 11 .Stability observations showed that each formula that had been observed for six cycles gave good results, namely no change in color, odor and phase separation. In general, an emulsion is considered physically unstable if all or part of the preparation forms a distinct layer on the surface or base of the emulsion in a preparation 16,17 . From irritation test, can be seen that the results of all cream scrubs do not cause irritation such as redness, swelling and itching of the volunteers' skin.The irritation test of a preparation is a very important test of the quality of the preparation after application, it should not irritate the skin in order to be accepted to be used 18 .…”

Section: Evaluation Results Of Cream Scrub Preparationsmentioning

confidence: 99%

“…The cause of dry skin is the lack of oil production by the skin's sebaceous glands. Some of the reasons for dry skin are environmental factors such as dry climate, sun exposure and population 17 . After using the ethanol extract cream of pandan wangi leaves for four weeks of use, it can be seen that the pandan wangi leaves ethanol extract cream scrub has an effect on improving skin smoothness.…”

Section: Moisture Effectiveness Test Resultsmentioning

confidence: 99%

See 1 more Smart Citation

The Effectiveness of Pandan Wangi Leaves (Pandanus Amaryllifolius Roxb.)Body Scrub Formulation in Smoothing the Skin

Leny

Diana

Ginting

et al. 2022

Asian J Pharm Res Dev

View full text Add to dashboard Cite

This study aims to formulate ethanol extract of pandan wangi leaves into a cream body scrub preparation and examining the effectiveness of body scrub in smoothing the skin by analyzing the moisture and evenness of volunteers' skin. This research was carried out by sample processing, extract making, formulating cream body scrub preparation by evaluating its consistency, color and odor (organoleptic), homogeneity, pH of preparation, spreadability, emulsion type, irritation test, stability and effectiveness test using skin analyzer. Cream scrub preparations were made with several concentrations, namely 1%, 2% and 3%. The results of the study showed that the ethanol extract of pandan wangi leaves (Pandanus amaryllifolius Roxb.) could be formulated in cream scrub preparations which show homogeneous preparations, pH ranging from 5.4-6.0, met the requirements for spreadability, was an oil in water emulsion type, did not irritate the skin and the preparations were stable during the accelerated stability test with cycling test method. Furthermore, the cream scrub preparations of Pandan wangi leaf extract can increase moisture and improve skin smoothness until 31.48% and show a significant different with another group test (p<0.05).

show abstract

Section: Evaluation Results Of Cream Scrub Preparationsmentioning

confidence: 99%

Section: Moisture Effectiveness Test Resultsmentioning

confidence: 99%

The Effectiveness of Pandan Wangi Leaves (Pandanus Amaryllifolius Roxb.)Body Scrub Formulation in Smoothing the Skin

Leny

Diana

Ginting

et al. 2022

Asian J Pharm Res Dev

View full text Add to dashboard Cite

show abstract

“…Dilakukan dengan mengamati perubahanperubahan yang meliputi bentuk, warna dan bau pada sediaan selama 24 jam [ 6].…”

Section: Pengamatan Organoleptikunclassified

“…Selanjutnya elektroda dicuci dengan menggunakan air dan dikeringkan. Pengukuran pH sediaan dilakukan dengan mencelupkan elektroda ke dalam hydrogel lalu dibiarkan sampai nilai yang menunjukan pH pada posisi konstan [6]. Nilai pH sediaan gel harus berkisar pada pH kulit yaitu 4,2 -6,5 tujuannya untuk mencegah terjadinya iritasi pada kulit [7].…”

Section: Pengukuran Phunclassified

Formulasi dan Uji Aktivitas Sediaan Plester Hidrogel Ekstak Etanol Daun Randu (Ceiba pentandra (L.) Gaertn) sebagai Antipiretik

Purwasih,

Endah,

Nofriyaldi

2023

J. Sains Kes.

View full text Add to dashboard Cite

Antipyretics are drugs that work by suppressing body temperature in a state of fever. Randu leaf (Ceiba pentandra (L.) Gaertn) is one of the plants that has activity as an antipyretic and can be formulated in the form of fever-reducing hydrogel patch transdermal preparations. This study aims to determine the physical properties of hydrogel patch drug of ethanol extract of randu leaves and to determine the antipyretic activity of hydrogel plaster preparations of ethanol extract of randu leaves against male white rat test animals (Rattus norvegicus) induced with 5% peptone. The method used is experimental method. The extract was formulated into a hydrogel plaster preparation with a dose variation of 150 mg (FI), 300 mg (FII), and 600 mg (FIII). Evaluation tests were carried out on preparations such as organoleptic, pH, weight uniformity, folding resistance, preparation thickness, and moisture absorption. The results showed that the ethanol extract of randu leaf can be formulated into a hydrogel plaster dosage form that meets the physical evaluation requirements. The antipyretic activity test of randu leaf ethanol extract has a percent (%) of antipyretic activity in FI (150 mg) of 1.91%, in FII (300 mg) of 2.93% and FIII (600 mg) with a percent (%) of 3.25%. This study can be concluded that the preparation of hydrogel plaster ethanol extract of randu leaves has met the requirements of a good evaluation and has the best antipyretic activity in formula III (600mg) with a percent (%) antipyretic activity of 3.25%. Keywords: Antipyretic, Randu leaf, Fever, Hydrogel patch, Transdermal drug Abstrak Antipiretik merupakan obat yang bekerja dengan cara menekan suhu tubuh pada keadaan demam. Daun randu (Ceiba pentandra (L.) Gaertn) ialah salah satu tanaman yang memiliki aktivitas sebagai antipiretik dan berpotensi diformulasikan dalam bentuk sediaan transdermal plester hidrogel penurun demam. Penelitian ini bertujuan untuk mengetahui sifat fisik sediaan plester hidrogel ekstrak etanol daun randu dan mengetahui aktivitas antipiretik sediaan plester hidrogel ekstrak etanol daun randu terhadap hewan uji tikus putih jantan (Rattus norvegicus) yang diinduksi dengan pepton 5%. Metode yang digunakan yaitu metode eksperimental. Ekstrak diformulasikan menjadi sediaan plester hidrogel dengan variasi dosis 150 mg (FI), 300 mg (FII), dan 600 mg (FIII). Dilakukan pengujian evaluasi sediaan seperti organoleptik, pH, keseragaman bobot, ketahanan lipat, ketebalan sediaan, dan daya serap kelembaban. Hasil penelitian menunjukan ekstrak etanol daun randu dapat diformulasikan dalam bentuk sediaan plester hidrogel yang memenuhi persyaratan fisik evaluasi. Uji aktivitas antipiretik ekstrak etanol daun randu memiliki persen (%) aktivitas antipiretik pada FI (150 mg) sebesar 1,91%, pada FII (300 mg) sebesar 2,93% dan FIII (600 mg) dengan persen (%) sebesar 3,25%. Penelitian ini dapat disimpulkan bahwa sediaan plester hidrogel ekstrak etanol daun randu telah memenuhi persyaratan evaluasi yang baik dan memiliki aktivitas antipiretik terbaik pada formula III (600mg) dengan persen (%) aktivitas antipiretik 3,25%. Kata Kunci: Antipiretik, Daun randu, Demam, Plester hidrogel, Sediaan transdermal

show abstract

“…Dibiarkan alat menunjukkan harga pH sampai konstan. Angka yang ditunjukkan pH meter merupakan pH sediaan [17].…”

Section: Pembahasanunclassified

Formulasi Krim Pelembab Kombinasi Ekstrak Lidah Buaya (Aloe vera) dan Ekstrak Kulit Manggis (Garcinia mangostana L.)

et al. 2022

Self Cite

View full text Add to dashboard Cite

Aloe vera contains flavonol compounds, saponins such as kaempeferol, quercetin and merycetin as much as 257.7, 94.80 and 1283.50 mg/kg, respectively. Saponins contained in Aloe vera gel are able to clean the dirt from skin. Vitamin E in aloe vera is also able to soften, moisturize and increase smoothness of the skin. Mangosteen peel waste contains higher xanthones compared to the mangosteen fruit itself. In 100 grams of mangosteen peel, there are 107.76 mg of xanthones which are an extraordinary nutritions for the skin because they act as antioxidants and antiaging. This study aims to formulate a combination of Aloe vera flesh extract and mangosteen peel extract into a cream dosage form and observe the effect in moisturizing the skin of volunteers within 3 months of treatment. The research was initiated by making extracts of Aloe vera and mangosteen peel by using the maceration method. Then the extract was formulated into cream preparations with varies concentrations of each cream A (0%:20%), cream B (5%:15%), cream C (10%:10%), cream D (15%:5%), cream E (20%:0%). The preparations were evaluated for their physical characteristics, namely homogeneity test, pH test, organoleptic test, dispersibility test, stability test, irritation test and its effectiveness in moisturizing volunteers skin using a moisture checker. The results showed that the combination extract of aloe vera flesh and mangosteen peel can be formulated in cream preparation that is homogeneous, does not change color, and remains stable in 12 weeks of storage with a pH between 6.0-6.6. The best cream formula in increasing moisture of skin are found in cream with a combination of 15% aloe vera flesh extract with 5% mangosteen peel extract by an uplifting until 92.5%.

show abstract

FORMULASI, KARAKTERISASI DAN UJI STABILITAS MIKROEMULSI MINYAK NILAM (Pogostemon cablin Benth.)

Cited by 8 publications

References 0 publications

The Effectiveness of Pandan Wangi Leaves (Pandanus Amaryllifolius Roxb.)Body Scrub Formulation in Smoothing the Skin

The Effectiveness of Pandan Wangi Leaves (Pandanus Amaryllifolius Roxb.)Body Scrub Formulation in Smoothing the Skin

Formulasi dan Uji Aktivitas Sediaan Plester Hidrogel Ekstak Etanol Daun Randu (Ceiba pentandra (L.) Gaertn) sebagai Antipiretik

Formulasi Krim Pelembab Kombinasi Ekstrak Lidah Buaya (Aloe vera) dan Ekstrak Kulit Manggis (Garcinia mangostana L.)

Contact Info

Product

Resources

About