Background: Visual Evoked Potential is the assessment of the visual pathway and the visual cortex. The present study was descriptive analysis of normal VEP between the age of 6 months to 4 years of age and the determination of the neuronal development among healthy children of above age group. Materials and Methods: The study was conducted in neurological lab of BPKIHS on healthy children (n=36) of well-baby clinic between the age of 0.5 to ≤4 years (yr). Subjects were divided into subgroup 1(0.5 to ≤2 yr), subgroup 2(2 to ≤3 yr) and subgroup 3(3 to ≤4 yr). Visual stimulator provided with fl ash light emitting diode (LED) goggle was used to stimulate the retina and VEP recording was done. Flash VEP parameters: latencies (N90, P120) and amplitude (N90-P120) were recorded. Post hoc (Bonferroni) analysis was done for comparing VEP variables. Pearson correlation were done for VEP with respect to age. Results: VEP latencies of children, age-group 3 to ≤4 yr showed signifi cantly less N90 latency on right eye stimulation comparing age-group 0.5 to ≤2 yr (103.75±22.54 vs. 79.09±17.77ms, p=0.012). P120 latency was signifi cantly less on right eye stimulation (148.5±15.38 vs.116.67±13.65ms p=0.001) and on left eye stimulation (145.91±18.11 vs. 116.67±13.65 ms, p=0.001) in age-group 3 to ≤4 yr children as compared to age-group 0.5 to ≤2 yr. Conclusion: Signifi cant decrement of VEP latencies as age advances which explains the maturation of central nervous system and functionally approaching to adult value at around 3 to 4 yr.

Background: Male and female brain develops differently. Gender is one of biological variables that influence visual evoked potentials (VEP). Some previous studies support the existence of sex related VEP difference while others not. This study is an attempt to explore if any difference exists in VEP responses between genders of children age seven to 10 years with an additional aim of documenting preliminary normative VEP data.Methods: This cross-sectional study was done on consenting children taken from parents (n=76; girls, n=41, age = 8.39±1.11years; boys, n=35, age =8.40±1.09 years). Pattern reversal VEP of these children was recorded as per standard method. Latencies of N75, P100, and N145 (ms); amplitude of P100 (μV) and ratio; interocular asymmetry (ms) of both eyes were calculated. Unpaired t-test was applied for statistical analysis. Ethical clearance was obtained prior to the study.  Result: Girls had decreased VEP latency of P100 than boys in left eye (108.15±8.42 vs. 112.71±11.17ms, p = 0.046), in right eye (107.71±8.52 vs. 114.46±10.98 ms, p = 0.004), and in combination of both eyes (107.92±8.07 vs. 113.58±10.36 ms, p = 0.009). Likewise, girls had decreased VEP latency of N75 than boys in right eye (67.44±6.77 vs. 71.29±8.07 ms, p = 0.027) and in combined eyes (67.23±5.19 vs. 70.14±7.31 ms, p = 0.047). A gender difference in P100 amplitude was not detected.Conclusion: Visual evoked potential differs with gender in prepubertal children aged seven to 10 years.

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