Metastasis of follicular thyroid carcinoma in a cervical lymph node associated with heterotopic ossification in a 34-year-old white female is presented. Pertinent gross and microscopic pathology is described and the literature is reviewed briefly. Bone formation in thyroid neoplasm has not been reported previously, except for bone metastases of medullary carcinoma.

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A 75-year-old man developed neurilemmoma of the left eighth cranial nerve, adenomatous polyp of the sigmoid colon, adenocarcinoma of the prostate, mixed cell type lymphoma of the right neck, and infiltrating ductal carcinoma of the right breast metachronously during a period of 38 years. The cancer of the right breast occurred 7 years after the long-term stilbestrol treatment of prostatic carcinoma, which suggests a causal relationship between the hormonal therapy and development of breast carcinoma.

A 75-year-old man developed neurilemmoma of the left eighth cranial nerve, adenomatous polyp of the sigmoid colon, adenocarcinoma of the prostate, mixed cell type lymphoma of the right neck, and infiltrating ductal carcinoma of the right breast metachronously during a period of 38 years. The cancer of the right breast occurred 7 years after the long-term stilbesterol treatment of prostatic carcinoma, which suggests a causal relationship between the hormonal therapy and development of breast carcinoma.