The growth of wireless networks has resulted in part from requirements for connecting people and advances in radio technologies. Wireless sensor networks are an example of these networks in which a large number of tiny devices interacting with their environments may be internetworked together and accessible through the Internet. As these devices may be scattered in an unplanned way, a routing protocol is needed. The RPL protocol is the IETF proposed standard protocol for IPv6-based multi-hop WSN. RPL requires that communication paths go through a central router which may provide suboptimal paths, not considering the characteristics of the applications the nodes run. In this paper is proposed an Application-Driven extension to RPL which enables to increase the WSN lifetime by limiting the routing and forwarding functions of the network mainly to nodes running the same application. As nodes may join a network at a non predictable time, they must be synchronized with respect to their application duty cycles. Therefore, nodes have to wake up and sleep in a synchronized way. In this paper it is also proposed such synchronization mechanism. The results confirm that the proposed solutions provide lower energy consumption and lower number of packets exchanged than the conventional RPL solution, while maintaining fairness and the packet reception ratio high.

Introduction:Diagnostic approaches to patients with a pleural effusion must be precise because many procedures depend on the nature of the fluid in the effusion. To date, no biochemical test is considered an appropriate alternative to Light’s criteria. This study compared the absolute pleural cholesterol (PC) level and the pleural cholesterol/serum cholesterol (PC/SC) ratio with Light’s criteria to determine exudative pleural effusions.Materials and Methodology:This study was a case series of 100 consecutive patients with pleural effusions. The clinical parameters that were used to diagnosis an exudative effusion included the cholesterol level, a pleural cholesterol level ≥ 50 mg/dL, a pleural/serum ratio ≥ 0.4, and Light’s criteria. The sensitivity, specificity, and positive and negative predictive values of each test for the diagnosis of an exudative effusion were assessed.Results:A total of 79 patients were definitively diagnosed with an exudative effusion and were included in the trial and analyzed. The mean PC level in the exudates was 90.39 mg/dL. The PC levels demonstrated a sensitivity of 97.22%, a specificity of 85.71%, a positive predictive value of 98.59% and a negative predictive value of 75%. The PC/SC ratio demonstrated a sensitivity of 81.48%, a specificity of 57.14%, a positive predictive value of 93.61% and a negative predictive value of 28.57%.Conclusion:The pleural cholesterol dosage level and the pleural/serum cholesterol ratio can be utilized as unique biomarkers to identify an exudative effusion and replace Light’s criteria.

The deployment of thousands of tiny devices inter-networked together and accessible through the Internet is the result of the increasing trend towards enabling the concepts of Internet-of-Things. As these devices may be scattered in a unplanned way, a routing protocol is needed. The RPL protocol is the IETF proposed standard protocol for IPv6-based multi-hop Wireless Sensor Networks (WSN). RPL requires that communication paths go through a central router which may provide suboptimal paths, making no distinction of the applications the nodes run. To address these issues, an Application-Driven extension to RPL is proposed which enables the increase of the WSN lifetime by limiting the routing and forwarding functions of the network mainly to nodes running the same application. This paper evaluates the proposed solution coded in ContikiOS by means of Cooja simulations, and compares it against regular RPL. Simulation results confirm that the proposed solution provides lower energy consumption, lower end-to-end delays, and lower total number of packets transmitted and received.