Workers should be considered as a vulnerable human subjects research population since they require special protections. The Code of Federal Regulations "Common Rule for the Protection of Human Subjects in Research" does not offer adequate definition of this issue. Currently there is no formal ethical framework that addresses the unique vulnerability of workers (or former workers) who participate in research studies. This article addresses this concern and is based on a larger report published by the U.S. Department of Energy. Further, even though workers may be study subjects for legitimate political, social, and scientific reasons, meritorious science and adherence to the Common Rule must be the expectation.

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Extraction, % 15 30 60 120 240 89.2 99.4 99.9 99.7 99.5 a Under conditions ae outlined in Procedure.The divalent CrO,-2 ion does not form an ion-association complex with the quaternary ammonium ion. Thus contact with caustic completely strips the chromium from the organic phase. Chromium could not be completely removed from methyl isobutyl ketone with the strip solution in the absence of the quaternary ammonium ion. This may be due to some type of solvation mechanism.Scavenging the strip phase with ferric hydroxide separates hydrolyzable ions that are coextracted with the chromium.Oxidization of the Cr(II1) in basic Plutonium Analytical solution appeared worthwhile and was investigated. A sample of aged fission products was treated according t o the first steps in the recommended procedure, followed by dissolution of the Cr(OH)a Mith 1 5 M NaOH. Sodium hypochlorite was added and after the oxidation was completed, an iron scavenging was performed. After filtering and acidifying, the Cr(Y1) n a s extracted according to the procedure. A ?-ray spectrum of the strip phase showed copious quantities of rutheniuni activity as well as some zirconiuniniobium activity in the final product. Apparently much of the ruthenium x i s in an extractable form and follon ed t!ie chrorniurn. Hence, in the recommended procedure, ruthenium is removed in the perchloric acid oxidation step. The yield is conveniently determined on a n aliquot of the strip phase by a spectrophotometric determination of chromate a t 370 mp.Decontamination by this procedure from 3-day and 3-month cooled fission product mixtures is shown in Figures 3 and 4, respectively. With irradiated stainless steel 300-type alloys, no foreign activity was found in the final chromium fraction.Six aliquots of chromium-51 activity were carried through the recommended procedure and the area under the 320k.e.17. photopeak m-as measured. The relative standard deviation was less than 1%. The average yield is 85% and the time of analysis is approvimately 1 hour. llTERATURE CITED(1) Dean, J. A., Beverlj-, lf. L., Ax41,.

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