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Swine were infected with Salmonella typhimurium, USDA #295, and treated with virginiamycin medicated feed continuously at a level of 55 g/metric ton for approximately 2 months. The incidence and persistence of shedding of this organism in the feces and in selected tissues were determined. No significant changes in the course of the infection were detected when virginiamycin treated animals were compared to nonmedicated infected controls. (

The anthelmintic agent methyl 5(6)-butyl-2-benzimidazolecarbamate (Parbendazole) was transformed to two of its animal metabolites, methyl 5(6)-(4-hydroxybutyl)-2-benzimidazolecarbamate and methyl 5(6)-3-(carboxypropyl)-2-benzimidazolecarbamate, by the filamentous fungus Cunninghamella bainieri ATCC 9244. The transformation pathway was shown to be through the 4-hydroxybutyl product to the 3-carboxypropyl product. The reaction favored accumulation of the latter product.