Squalene, [oxidized form squalane] is a terpenoid with biological activity that produced by animals and plants. In the human body, a significant excretion named as sebum includes squalene in 12 percent. This bioactive compound shows anti-inflammatory, detoxifying, moisturizing and antioxidant effects on the human body. In addition to having these properties, it is known that squalene production decreases as less sebum is produced with age. Because of that, the need for supplementation of squalene through products has arisen. As a result, squalene production has been drawn attention due to its many application possibilities by cosmetic, cosmeceutical and pharmaceutical fields. At this point, approximately 3,000 of sharks, the major and the most popular source of squalene must be killed to obtain 1 ton of squalene. These animals are on the verge of extinction. This situation has caused to focus on finding microalgae strains, which are sustainable producers of squalene as alternative to sharks. This review paper summarizes the recent progresses in the topic of squalene. For this purpose, it contains information on squalene producers, microalgal squalene production and cosmetic evaluation of squalene.
Algae are recognized as the main producer of commercial alginate. Alginate produced using algae is located in the walls and intracellular regions of their cells. Its properties vary depending on the species, growing and harvesting seasons, and extraction methods. Alginate has attracted the attention of several industries, thanks to its unique properties such as its biodegradability, biocompatibility, renewability and lack of toxicity features. For example, it is considered a good encapsulation agent due to the transparent nature of the alginate matrices. Also, this biopolymer is recognized as a functional food in the food industry. It can be tolerated easily in human body and has the ability to reduce the risk of chronic diseases. Besides, it is used as an abrasive agent, antioxidant, and thickening and stabilizing agents in cosmetic and pharmaceutic industries. Generally, it is used in emulsion systems and wound dressing patches. Furthermore, this polysaccharide has the potential to be used in green nanotechnologies as a drug delivery vehicle via cell microencapsulation. Moreover, it is suitable to adopt as a coagulant due to its wide range of flocculation dose and high shear stability. In this chapter, the mentioned usage areas of algal alginate are explained in more detail.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.