No abstract

Haritakyadi eye drops are prepared by hydro-distillation (Arka kalpana) of ingredients like Terminalia chebula Retz. (Haritaki), Emblica officinalis Linn. (Amalaki), Berberis aristata Dc. (Daruharidra) and Glycyrrhiza glabra Linn. (Yastimadhu). The research was designed to explore the volatile constituents by Gas Chromatography-Mass Spectrometry (GC-MS). Secondary metabolite screening using GC-MS revealed the presence of fifteen constituents. Out of fifteen constituents 8 could not be identified and remaining 7 compound identified as 1

Polyherbal formulations (PHFs) are potential for their safety, cost effectiveness and better acceptability than allopathic drugs. PHFs help in amelioration of various serious disorders. Therapeutic efficacy of herbal medicine is exerted due to the bioactive constituents of plants. The present study was aimed to prepare and standardize a polyherbal formulation (Vachadi syrup) including traditional drugs such as Acorus calamus (rhizomes), Trachyspermum ammi (fruits), Phyllanthus emblica (fruits), Terminalia bellirica (fruits), Terminalia chebula (fruits), Zingiber officinalis (rhizomes). Methods: Prepared polyherbal formulation was subjected to determine the physical constants (pH determination, refractive index, specific gravity, total solids, reducing and non reducing sugar) and HPTLC fingerprinting. Results: The analysis revealed the physical constant such as refractive index 1.43418, specific gravity 1.256, pH 3.5, total solids 61.50, total sugar 17.64 and reducing sugar 4.46. HPTLC fingerprinting profile showed different band patterns at different wavelength under short UV, long UV and at 620nm after derivatisation with vanillin sulphuric acid spraying reagent. Unique Rf patterns were recorded. Conclusion: Vachadi syrup was authenticated according to pharmacopeial standards as its analysis was important to ensure the quality of drug.

Pratishyaya is one among the Nasagata roga & is a complex disease involving several symptomatology and diverse pathogenesis. It is one of the common disorders of children known for its recurrence and chronicity. It could lead to complications such as Kasa, Shwasa then Kshaya if not managed in time. Recurrence of this disease can be attributed to lower level of immunity in children due to Asampurna bala and hence we need such a drug to improve the immunity to prevent recurrence and complications. Vachadi syrup is one such medi cine which serves the purpose, with this aim this trial has been taken up. It is an open labeled clinical trial where 30 children of age group 4-12 yrs with the signs and symptoms of Pratishyaya were enrolled. Vachadi syrup was given in a dose of 5ml 8 th hourly for 4-8yrs and 10ml 8 th hourly for 8-12yrs for 7 days, clinical assessment was done by grading both subjective and objective criteria. Vachadi Syrup shows highly significant results in clinical symptoms of Pratishyaya & laboratory investigations. Pratishyaya is the disease condition in which Vata and Kapha vitiation is observed, Vachadi sryup shows the dominancy of Tikta, Kashaya and Katu Rasa, Ushna Virya(hot potency), Katu Vipaka (post digestion) which helps in alleviating Vata & Kapha by breaking down the pathogenesis. The clinical trial suggested that the Vachadi syrup is effective and safe herbal formulation in reducing the signs and symptoms of Pratishyaya.

Atopic dermatitis (AD) is a common, chronic skin disorder that can significantly impact the quality of life of affected individuals as well as their families. Not only patients are affected by the social stigma of a visible skin condition, but the intense itching characteristic of the disease often leads to significant sleep disturbances. If the itch can be controlled, the rash can be more readily treated. As per Ayurvedic classics, Atopic dermatitis can be incorporated under the category of twak vikara (skin disease). In this article, a case of 7 year old boy with dry, itchy and scaly skin with excoriative lesions who was treated with parisheka (affusion sudation) and internal medicaments. The parisheka (affusion sudation) was prepared out of Karanja (Pongamia pinnata Pierre.) and Nimba patra (Azadirachta indica A. Juss.) which are kushtahara (alleviates skin lesions) and kandughna (anti-pruritic). Encouraging results were observed in the form of reduction in itching and dryness of skin.