Objectives:The study evaluated the efficacy of an internetdelivered cognitive-behavioral intervention for caregivers of people with dementia and examined acceptance of program characteristics.Method: Thirty-nine caregivers (M age = 62.11 ± 9.67, 78.4% female) were enrolled in a 2 × 3 randomized-controlled trial (RCT) that compared an intervention and wait-list control group. A cognitive-behavioral intervention program was adapted for delivery via an internet platform. Participants exchanged eight weekly messages with a therapist.Results: Treatment satisfaction and acceptance of the program were high. Well-being increased over the intervention duration and intervention group participants were better able to cope with the anticipated death of the care recipient and utilized more psychosocial resources after the intervention ended. Effects were not maintained until follow-up and there were no treatment effects for depression and burden of care. Conclusions: Internet-delivered cognitive-behavioral interventions are suitable for caregivers. A larger RCT needs to investigate possible combinations of classic and internetdelivered programs and confirm efficacy. K E Y W O R D S acceptability, caregiving, cognitive-behavioral therapy, dementia, internet interventions, treatment satisfaction J. Clin. Psychol. 2019;75:594-613. wileyonlinelibrary.com/journal/jclp 594 |

Prosta Fink Forte^(r) in the Therapy of Benign Prostatic Hyperplasia. Multicentric Surveillance Study in 2,245 Patients Objective and Design:Therapeutic use and safety of a pumpkin seed extract were tested in a multicentric clinical trial. Patients and Methods:2,245 patients suffering from benign prostate hyperplasia (stage I to II according to Alken) received for 12 weeks 1–2 capsules Prosta Fink Forte per day. Urinary symptoms were recorded by the International Prostate Symptom Score according to the American Urological Association (I-PSS), the influence on quality of life has been recorded by a quality of life questionnaire (LQ Index). Results:The I-PSS decreased by 41.4%, life quality improved by 46.1% during therapy. More than 96% of the patients reported no undesired side effects under the treatment with Prosta Fink Forte. Conclusion:Prosta Fink Forte facilitates an efficient improvement of BPH symptoms, especially in early stages.

Introduction: Long-term outcomes are of particular importance in evaluating interventions for family caregivers of people with dementia (PwD). So far, evidence for long-term effects (>6 months postintervention) is limited to four interventions. Objective: We examined the long-term effects of Tele.TAnDem, a telephonebased cognitive-behavioral therapy (CBT) intervention, on a variety of outcomes at 3-year follow-up, the longest follow-up of any intervention study for caregivers of PwD (without continuous support). Methods: Caregivers of PwD were randomly assigned to receive Tele.TAnDem consisting of 12 sessions over 6 months (intervention group [IG]) or usual care (control group [CG]). At 3-year follow-up (i.e., 2.5 years postintervention), 29 caregivers in the IG and 22 caregivers in the CG were still caring at home for a PwD. Results: Caregivers in the IG reported significantly lower caregiver burden and higher quality of life regarding social relationships. Conclusions: Tele.TAnDem is successful in buffering detrimental effects of caregiving on caregiver burden and social relationships in the long term. The small-to medium-sized effects lie in the range of effect sizes reported in the few previous investigations. The findings add to the scant evidence that interventions yielding long-term outcomes have to date mostly been multicomponent interventions based on CBT principles with structured techniques and at least seven sessions over more than 2 months. Public Health Significance StatementEvidence for long-term effects of interventions for family caregivers of people with dementia is limited to four interventions. This study suggests that Tele.TAnDem, a telephone-based cognitivebehavioral intervention, is successful in buffering detrimental effects of caregiving on caregiver burden, and quality of life regarding social relationships of family caregivers of people with dementia in the long term (i.e., 2.5 years after therapy). The findings add to the scant evidence that interventions yielding long-term outcomes have to date mostly been multicomponent interventions based on the principles of cognitive-behavioral therapy with structured techniques and at least seven sessions over more than 2 months.

Background Providing care for someone with a disease or chronic condition can have a negative psychological, physical, social, and economic impact upon informal caregivers. Despite the socio-economic relevance and more than three decades of caregiver intervention research only very few translational efforts of successful interventions are reported. Still less of these interventions have been implemented into routine services. The aim of the ReDiCare study (German acronym BerTA) is to evaluate the effectiveness of a stepped counselling approach for burdened caregivers delivered by care counsellors of two long-term care insurances and registered psychotherapists. Methods/ design A pragmatic randomised controlled trial with 572 caregivers of older adults (≥ 60 years) receiving benefits of one of the two participating long-term care insurances. Participants are assigned (t0) to either the ReDiCare intervention or a control group receiving routine care and counselling. Data are collected at baseline (-t1), 3-month (t1), 9-month (t2) and 15-month (t3). The 9-month post-intervention assessment (t2) is the primary endpoint to evaluate the results on the primary and secondary outcomes, measured by self-reported questionnaires. Depressive symptoms measured with the CES-D are the primary outcome. The main secondary outcomes are physical complaints, utilization of psychosocial resources, caregiver self-efficacy and burden, positive aspects of caregiving and perceived care quality. A process evaluation, including audio tapes, self-report questionnaires and documentation will be conducted to examine internal and external validity of the intervention. Data on direct and indirect costs are collected for the (health) economic evaluation, using a health care perspective and a societal perspective. Discussion While comparable previous caregiver interventions have been developed and evaluated for specific caregiver groups (e.g. dementia caregivers, stroke caregivers), the ReDiCare study will indicate whether a stepped approach will be effective also in a broader group of caregivers. The intervention is one of the very few translational studies in caregiver intervention research and will provide valuable insights into relevant factors for training, intervention protocol adherence, effectiveness, and costs for future implementation steps. Trial registration Deutsches Register Klinischer Studien (German Clinical Trials Register), DRKS00014593 (www.drks.de, registered 14 May 2018) and International Clinical Trials Registry Platform, DRKS00014593  (https://apps.who.int/trialsearch/).

Objectives Despite its efficacy, little is known about what makes Internet‐based cognitive behavioral therapy (iCBT) effective. We, therefore, analyze participants' and therapists' experiences of Grawe's five general change mechanisms (alliance, resource activation, clarification, problem actuation, mastery) during an iCBT intervention for family dementia caregivers, and how their experiences were related to treatment outcomes. Method Participants (N = 30) exchanged eight weekly messages with a therapist via an Internet platform. We used the Bern Post Session Report to assess participants' and therapists' experiences of the general change mechanisms after each session. Results Treatment outcomes were associated with therapists' overall experiences of alliance, clarification, and mastery. Participants experienced more problem actuation than therapists. Only participants' and therapists' experiences of clarification over time differed. Conclusions Grawe's general change mechanisms are also relevant for iCBT. We recommend considering Grawe's framework when designing Internet‐based therapeutic interventions and when training therapists to deliver such interventions.