The
design and use of materials in the nanoscale size range for addressing
medical and health-related issues continues to receive increasing
interest. Research in nanomedicine spans a multitude of areas, including
drug delivery, vaccine development, antibacterial, diagnosis and imaging tools, wearable
devices, implants, high-throughput screening platforms, etc. using biological, nonbiological, biomimetic, or hybrid materials. Many of these
developments are starting to be translated into viable clinical products.
Here, we provide an overview of recent developments in nanomedicine
and highlight the current challenges and upcoming opportunities for
the field and translation to the clinic.
Magnetic drug targeting employing nanoparticles as carriers is a promising cancer treatment avoiding side effects of conventional chemotherapy. We used iron oxide nanoparticles covered by starch derivatives with phosphate groups which bound mitoxantrone as chemotherapeutikum. In this letter we show that a strong magnetic field gradient at the tumour location accumulates the nanoparticles. Electron microscope investigations show that the ferrofluids can be enriched in tumour tissue and tumour cells.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.