The objective of this study was to investigate whether metabolic tumor volume (MTV) by positron emission tomography (PET) can be a potential prognostic tool when compared with Ann Arbor stage, in stages II and III nodal diffuse large B cell lymphoma (DLBCL). We evaluated 169 patients with nodal stages II and III DLBCL who underwent measurements with PET prior to rituximab combined with cyclophosphamide, adriamycin, vincristine, and prednisone (R-CHOP). Cutoff point of MTV was measured using the receiver operating characteristic (ROC) curve. During a median period of 36 months, stage II was 59.2% and III was 40.8%. Using the ROC curve, the MTV of 220 cm3 was the cutoff value. The low MTV group (<220 cm3) had longer progression-free survival (PFS) and overall survival (OS), compared with the high MTV group (≥220 cm3) (p < 0.001, p < 0.001). Stage II patients had longer survival than those in stage III (PFS, p = 0.011; OS, p = 0.001). The high MTV group had lower PFS and OS patterns, regardless of stage, compared with the low MTV group (p < 0.001, p < 0.001). Multivariate analysis revealed an association of the high MTV group with lower PFS and OS (PFS, hazard ratio (HR) = 5.300, p < 0.001; OS, HR = 7.009, p < 0.001), but not stage III (PFS, p = 0.187; OS, p = 0.054). Assessment of MTV by PET had more potential predictive power than Ann Arbor stage in the patients that received R-CHOP.
The oil and gas (O&G) industry suffers from a negative perception of poor sustainability. O&G companies are therefore engaged in several socially sustainable activities related to community development and environmental protection. This article determines whether the social, environmental, and economic dimensions of corporate social responsibility (CSR) are equally value-additive to O&G companies. We measure the company-specific level of CSR activities from the information provided in the annual financial reports of O&G companies and determine the effects of CSR dimensions on firm value. We find that CSR enhances firm value of O&G companies. While social activities such as employee well-being and community development are key value-drivers, environmental and economic sustainable activities have an insignificant impact on the market value of O&G companies.
RésuméL'industrie pétrolière et gazière (O&G) souffre de la perception négative qu'on a de sa faible durabilité. C'est pourquoi les sociétés du secteur pétrolier et gazier s'investissent dans plusieurs activités socialement durables liées au développement communautaire et à la protection environnementale. Dans cet article, nous nous interrogeons sur la valeur ajoutée liée aux dimensions sociales, environnementales et économiques de la responsabilité sociale des entreprises (CSR) de ce secteur. Nous mesurons le niveau d'activité de la CSR de l'entreprise à partir des informations disponibles dans les rapports financiers annuels des sociétés pétrolières et gazières et déterminons les effets des dimensions de la CSR sur la valeur de l'entreprise. Les résultats montrent que la CSR augmente la valeur des sociétés pétrolières et gazières. Par ailleurs, tandis que les activités sociales telles que le bien-être des employés et le développement communautaire sont des facteurs clés de valeur, les activités environnementales et économiques durables n'ont qu'une incidence négligeable sur la valeur marchande des sociétés pétrolières et gazières
This paper considers the usability of mobile applications operating within a new logistics domain referred to as logistics in life (LIL). The LIL sector has primarily been capitalized on by logistics startups which develop mobile applications or “apps” to provide customized services that penetrate niche spaces outside the reach of traditional logistics firms. The objective of this study is to evaluate whether LIL apps meet usability standards that satisfy users’ experiences. As a way to improve usability, problems should be identified through proper measurement and evaluation methods. To derive usability scores, usability testing targeting representative apps from Korea and foreign countries was conducted. The relationship between usability and user interest for each app was determined through big data analytics followed by recommended improvement strategies.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.