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In this experimental research, thin polyurethane films containing reactive functional groups (hydroxyl and amino groups) were synthesized. The raw materials used in the synthesis are: a hydroxyl component (Elastoflex W5516/115) and an isocyanate component (semiprepolimer type) based on 4,4'- diphenylmethane-diisocyanate (MDI) or toluene-2,4-diisocyanate (TDI). Two different antibiotics were adsorbed on these films: amikacin and ceftazidime which formed physical bonds with the polyurethane matrix. The films were characterized by SEM, DMA and a culture of Escherichia coli and a counting room was used in order to determine the antimicrobial efficiency.

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