A group of 31 patients with inverted papilloma were treated at the Mount Sinai Medical Center. There were no multicentric cases, and one patient had an associated malignancy. A conservative procedure consisting of intranasal or transantral sphenoethmoidectomy was selectively performed in 8 patients with limited lesions. No recurrences were observed in this group after a mean follow-up of 2 years. Lateral rhinotomy with medial maxillectomy and en bloc resection of the ethmoid labyrinth was performed in 23 other patients. One recurrence appeared in this group, members of which were followed a mean of 3.8 years. Radiographic evaluation by multidirectional polytomography and CT scanning permits identification of a small group of patients who have limited lesions and may be candidates for conservative tumor excision.

Although the carotid body is an established chemoreceptor, there is considerable evidence also for its possessing a secretory function. While adrenergic neuroendocrine cells of neuroectodermal derviation exist in the central and autonomic nervous systems, the exact histogenesis of the mammalian carotid body is unsettled. The normal human carotid body and glomus jugulare tumor have been grown in tissue culture and their constituent cells have been observed to transform from epithelial to neuronoid appearing cells with extensive dendritic processes. This conversion has been further enhanced by the addition of nerve growth factor, a polypeptide specific for neural tissue. Electron microscopy confirmed that these culus cell. Histofluorescence revealed that these in vitro cells continued to synthesize and store biogenic monoamines in culture. Comparison of the morphologic, ultrastructural and histochemical features of the glomus cell with established neuroendocrine cells (central nervous system neurons, sympathetic ganglia cells, chromaffin cells) shows striking similarities. On the basis of these findings it is concluded that the glomus cell is a modified neuron of neural crest origin. The embryology, electron microscopy and histochemistry of the carotid body and related glomera and their tumors are reviewed.

The clinical findings in a series of eighteen dogs with brachial plexus avulsion are presented. It is suggested that both motor and sensory loss reflects damage in nerve roots and ventral branches, rather than the peripheral nerves. Ipsilateral loss of the panniculus reflex with a consensual response was a common finding. Fifty‐five per cent of the dogs also showed sympathetic dysfunction with an ipsilateral myosis. Further methods for investigating these cases are also discussed. Résumé. Sont présentées les observations cliniques sur une série de 18 chiens attents d'avulsion du plexus brachial. Il est suggéré que les pertes moteur comme sensorielles proviennent de dommages causés aux racines nerveuses et aux branches ventrales, plutôt qu'aux nerfs péri‐phériques. La perte du réflexe pannicule avec réponse consensuelle fut communément observée. Chez 55% des chiens il existait aussi une dysfonction sympathique avec myosis ipsilatéral. Autres méthodes d'investigation de ces cas sont également discutées. Zusammenfassung. Die klinischen Befunde einer Serie von achtzehn Hunden mit Ausreissung des Plexus brachialis sind wiederlegt. Es ist vorgeschlagen, dass der Bewegungs‐ und Empfin‐dungs‐ Verlust eine Beschädigung der Nervenwurzeln und ventralen Nervenästen, nicht der peripheralen Nerven, reflektiert. Selbseitiger Verlust des Pannicules Reflexes, mit gleichsinniger Respondierung, wurde allgemein erwiesen. An 55% der Hunde konnte sympathetische Dysfunktion, mit selbseitiger Myose, beobachtet werden. Weitere Untersuchungsmethoden dieser Fälle, sind ebenfalls ausgeführt.

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