Urinary methylmalonate excretion is increased in rats with an insufficiency of vitamin B(12). Excretion of methylmalonate is not affected by folic acid, vitamin E, or selenium, but is markedly decreased by small amounts of vitamin B(12) added to the diet.
A quantitative method for the determination of urinary phenols is described. Data obtained in 20 children by this method are similar to averages in adults obtained by others. This is exceeded by the excretion of a phenylketonuric infant when placed on excessive intakes of phenylalanine.
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