Lipodystrophies are a group of rare disorders of diverse aetiology characterised by variable body fat loss. The loss of body fat may affect nearly the entire body (generalised), only certain body regions (partial) or small areas under the skin (localised). Body fat loss can result from underlying genetic defects, autoimmune mechanisms, or drugs. Progressive lipodystrophy is a chronic, inflammatory, degenerative disease of the connective tissue. It leads to the blockage of the circulation and lymphatic drainage, followed by an accumulation of toxins, which promote hyperplasia of the fat cells. As a consequence, connective tissue rigidity promotes skin dimpling or orange skin. This study was designed to evaluate the efficiency of Endolift®, a novel minimally invasive outpatient laser procedure, for the treatment of Progressive Lipodystrophy. 30 women showing cellulite, in the range of 20 to 55 y-o, were enrolled for this study. Patients have undergone a single treatment under tumescent anaesthesia. Treatment was performed using the Endolift® procedure, consisting of the device Eufoton® LASEmaR® 1500. In addition, a 1470-nm wavelength laser was utilised, lead by micro-optical fibres of different calibres directly inside the skin. This treatment aims to destroy and remove degenerative connective tissue and promote neocollagenesis. Optimal results were obtained by 23 patients, 5 had good results, and 2 reported moderate results. No side effect was recorded. Adipocytolysis was performed on 6 patients and we removed 50 to 350 ml of fat. Even after 3 years, 80% of patients maintain significant results. These data show that Endolift® laser treatment represents one of the most effective treatments for removing Progressive Lipodystrophy.

This study was designed to evaluate the efficiency of Endolift®, a novel minimally invasive outpatient laser procedure, for the nonsurgical treatment of eyelid ptosis. Thirty patients aged 30 to 55, 15 women and 15 men, were enrolled on this study. All patients had skin ptosis of the upper eyelids and the eyebrow area and dropping of the lateral part of the eyebrow. Patients have undergone a single treatment under micro drops of local anaesthesia. Treatment was performed using the Endolift® procedure, consisting of the device Eufoton® LASEmaR® 1500. This device uses a 1470 nm wavelength laser lead by micro-optical fibres of different calibres directly inside the skin. Twenty-four reported optimal results, 4 very good and 2 moderate. The first results were visible after 5 to 14 days and improved over time, and the average downtime was between 2 and 3 days due to the swelling. No other side effects were observed. These data confirm that Endolift® is a safe and effective procedure for the nonsurgical treatment of eyelid ptosis representing a real alternative to surgery.

Hidradenitis suppurativa, also known as acne inversa, is a chronic inflammatory skin disease which affects ~1% of the world population. Hidradenitis suppurativa significantly impacts patients’ quality of life due to its chronic nature and frequently occurring relapses. Therefore, Hidradenitis suppurativa patients need to get an early diagnosis. This study was designed to evaluate the efficiency of Endolift®, a novel minimally invasive outpatient laser procedure, for treating Hidradenitis suppurativa. Thirty patients in the range of 19 to 43 y-o, 20 women and 10 men, were enrolled on this study. Patients have undergone a single treatment under tumescent anaesthesia. Treatment was performed using the Endolift® procedure, consisting of the device Eufoton® LASEmaR® 1500. This device uses a 1470 nm wavelength laser lead by micro-optical fibres of different calibres directly inside the skin. This treatment aims to destroy problematic glands with a thermal effect and remove them with liposuction. The treatment has a strong anti-inflammatory effect and promotes neocollagenesis. Eighteen patients obtained optimal results, 5 had good results, and 7 reported moderate results. The treatment was repeated for 7 patients for small refractory areas. Patients with earlier onset of the disease generally had better results. No side effect was recorded. Endolift® treatment represents a big hope for the patient because it is a safe, effective, minimally invasive procedure and can be repeated.