This study examines the current status of immunization among 0-3 year old children in Bakersfield and identifies barriers that prevent families from immunizing their children. A survey research design using a stratified sampling method was employed to collect data from 207 randomly selected English and Spanish speaking households having at least one child between the ages of 0-3 in Bakersfield. The findings reveal that 49% of the parents had no shot cards regarding children's immunization status. However, a significant majority of them immunized their children despite having no records. The most commonly reported consumer related barrier for late immunization was having a sick child followed by lack of parental memory and fear of side effects. The major provider-related barriers included lack of an opening for an appointment with the health care provider, limited clinic hours, and long lines in clinics. Lack of transportation was the single most systemic barrier. These findings suggest that reminder calls, increased transportation, weekend clinics and better rapport with parents can improve the immunization rates in ethnically diverse rural communities.

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High performance liquid chromatography procedures have been developed for the assay of propofol-thiopental sodium and propofol-ondansetron mixtures. The separation and quantitation of propofol-thiopental sodium were performed on a stable bond phenyl column at ambient temperature using a mobile phase of 55:45 v/v aqueous 0.01 M monobasic postassium phosphate pH 4 -acetonitrile at a flow rate of 1 mL/min, with detection set at 235 nm. The separation was achieved within 20 min. Propofol and thiopental sodium were linear in the 12.7 -38 and 31.4 -94 pg/mL ranges, respectively. Accuracy and precision were in the range 0.2 -2.6 and 0.2 -3.2%, respectively, for the two analytes and the limits of detection for propofol and thiopental sodium were 1210 and 317 ng/mL, respectively, based on a signal to noise ratio of 2 and a 20 pL injection. The separation and quantitation of the propofol-ondansetron mixture was achieved on a 10 vm particle size phenyl column.,using a mobile phase of 50:50 v/v aqueous 0.01 M monobasic potassium phosphate pH 4 -acetonitrile at a flow rate of 1 mL/min, with detection set at 268 nm. The separation was achieved within 15 min. Propofol and 2285 Copyright 0 1996 by Marcel Dekker. Inc Downloaded by [UQ Library] at 05:31 04 November 2014 2286 KING ET AL.ondansetron were linear in the 2.5 -37.5 and 0.48 -7.2 pg/mL ranges, respectively. Accuracy and precision were in the range 0.4 -2,4 and 0.2 -0.6%, respectively, for the two analytes and the limits of detection for propofol and ondansetron were 1 17 and 6 1 ng/mL, respectively, based on a signal to noise ratio of 2 and a 20 pL injection.

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