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During recent decades, th interest in renewable, biodegradable, non-fossil materials has been exponentially increasing. Thus, cellulose and cellulose-derived products have been extensively considered for a wide variety of new potential uses. Due to the sustainability of cellulosic raw materials and their excellent properties, the use and modification of cellulose-based materials can be versatile in the material science and technology community. In this featured article, the fundamentals and background of cellulose-based gels are presented, and approaches, prospects and developments in the field, including their potential future applications, are discussed.