As the almost 200-year palaeontological research revealed, the geographical distribution of various fossil mollusk faunas in deposits of the late Neogene Lake Pannon displays a regular pattern. The lake basin was filled by lateral accretion of sediments, resulting in condensed sedimentary successions in the distal parts of the basin and successively younger shallow-water deposits from the margins towards the basin center. Exposed intra-basin basement highs, however, broke this strict pattern when they acted as sediment sources during the lake’s lifetime. The Mecsek Mts in southern Hungary was such an island in Lake Pannon during the early late Miocene. Deposition of the 200 m thick Sarmatian–Pannonian sedimentary succession in Pécs-Danitzpuszta at the foot of the Mecsek Mts was thus controlled by local tectonic and sedimentary processes, resulting in a unique succession of facies and mollusk faunas. A typical, restricted marine Sarmatian fauna is followed by a distinct freshwater or oligohaline interval, which, according to micropalaeontological evidence, still belongs to the Sarmatian. Although poor preservation of fossils does not allow firm conclusions, it seems that freshwater Sarmatian snails were the ancestors of the brackish-water-adapted early Pannonian pulmonate snail taxa. The successive “Sarmatian-type” dwarfed cockle fauna is similar to those widely reported from the Sarmatian–Pannonian boundary in various parts of the Pannonian Basin; however, a thorough taxonomic study of its species is still lacking. The bulk of the sedimentary succession corresponds to the sublittoral to profundal “white marls,” which are widespread in the southern Pannonian Basin. In Croatia and Serbia, they are divided into the Lymnocardium praeponticum or Radix croatica Zone (11.6–11.4 Ma) below, and the Congeria banatica Zone (11.4–9.7 Ma) above; this division can be applied to the Pécs-Danitzpuszta succession as well. Sedimentation of the calcareous marl, however, ceased at Pécs-Danitzpuszta at about 10.5–10.2 Ma ago (during the younger part of the Lymnocardium schedelianum Chron), when silt was deposited with a diverse sublittoral mollusk fauna. Similar faunas are known from the Vienna Basin, southern Banat, and other marginal parts of the Pannonian Basin System, but not from Croatia and Serbia, where deposition of the deep-water white marls continued during this time. Finally, the Pécs-Danitzpuszta succession was capped with a thick, coarse-grained sand series that contains mollusk molds and casts representing a typical littoral assemblage. This littoral fauna is well-known from easternmost Austria, northern Serbia, and northwestern Romania, but never directly from above the sublittoral L. schedelianum Zone. The fauna is characteristic for the upper part of the Lymnocardium conjungens Zone and has an inferred age of ca. 10.2–10.0 Ma. The Pécs-Danitzpuszta succession thus allows to establish the chronostratigraphic relationship between mollusk faunas that have not been observed in one succession nor in close proximity to each other in other parts of the Pannonian Basin.