On March 11, 2020, the World Health Organization declared COVID-19 apandemic. Despite a large number of scientific publications concerning the clinical picture and trea tment methods, data on structural changes of internal organs in COVID-19 is still insufficient. This review presents and analyzes several clinical cases published by research groups in various countries. COVID-19 infection is caused by a SARS-CoV-2 virus that binds to the angiotensin-converting enzyme 2 ACE2 receptor. Interaction with this receptor is the initial stage of pathogenesis. The morphological picture is similar to pneumonia caused by SARS-CoV and MERS-CoV: at the initial stage, a picture of shock lungs develops, later it ends in fibrosis and organizing pneumonia. One of the most severe complications is acute respiratory distress syndrome, which is observed in some clinical cases reviewed. In this article, we collected cases of clinical and morphological studies of patients with COVID-19, published in international peer-reviewed medical literature to date.

The topic of the development of suicidal behavior has remained relevant for many years. Every year there are more and more reports of new morphological changes in brain tissue. The presented analytical review of the literature concerns the state of the issue of studying the morphology of macroglia, astrocytes, oligodendrocytes and the blood-brain barrier in suicide. Determining the characteristic morphology of death due to suicide can potentially become an evidence base for confirming or excluding factors of suicide development when assessing the causes of death. Further research is needed to form a clearer picture of the changes in relation to the practice of forensic medical examination.

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