These data indicate that surgical margin status is an independent predictor of PSA recurrence and secondary cancer treatment in patients who underwent radical prostatectomy as definitive local therapy for prostate cancer.

No abstract

Approximately 1 in 5 patients receive second cancer treatment within a mean of 3 years following initial local treatment for prostate cancer. Our data suggest that the likelihood of receiving second treatment was lowest in patients initially treated with radical prostatectomy.

No abstract

and Medicine for their assistance on the mathematical history of the cycloid, and Ethan M. Coven of the Wesleyan University Department of Mathematics for his help with symmetry theory. Robert J. White provided invaluable technical assistance. Requests for reprints should be sent to Dennis R.