The aim of the present study was to investigate the effect of a short period of supplementation with glutamine dipeptide (GDP) on the acute responses to resistance training on the executive functions of people with HIV/AIDS. The sample consisted of 10 HIV+ women (45.00 ± 12.77 years old; 65.71 ± 12.04 kg; 1.54 ± 0.05 m) who were submitted to a randomized double-blind crossover procedure according to two experimental conditions: orally supplemented with 20 g/day of GDP or with maltodextrin for seven days. On the seventh day of supplementation all participants did cognitive function tests before and immediately after a resistance training session. Seven days of washout were adopted between conditions. Stroop and N-back tests were used to evaluate the executive functions. The training reduced the response time of each card in isolation and the latency time among them. GDP supplementation increased the magnitude of this effect, thus, reducing the latency time from the first to the last card in the Stroop test by almost 50% (P < 0.01). Considering the N-back test, there were no significant differences. It is suggested that GDP supplementation may increase the magnitude of the effect of an acute resistance training session in cognitive functions, particularly in the inhibitory control of people with HIV/AIDS. This trial is registered with NCT03236532.

People living with HIV are at an increased risk of developing cognitive deficits. Physical exercise is an important strategy to improve the brain health of people living with HIV. This randomized, controlled study aimed to investigate the acute effect of a single resistance exercise session on the cognitive function of people living with HIV. Twenty-three people living with HIV were randomized (1:1) to a control group (n = 12) or the exercise group (n = 11). Cognitive function was assessed by the Stroop test and the Trail Making Test. The exercise group was evaluated before and after the exercise session; meanwhile, the control group was evaluated before and after a 40-minute rest period. No statistical difference was found on the effect of exercise on cognitive function ( p > 0.05). This result suggests that one session of resistance exercise was not capable of improving the cognitive function of people with HIV.

The aim of this study was to verify blood pressure (BP) responses after a single resistance exercise session in women with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS). Twelve patients underwent a resisted exercise session. BP, heart rate, and rate pressure product were evaluated before and during 120 min after the session. Mean cardiovascular values before and after the session were similar (P>0.05). Analysis of the individual data revealed that for 120 min after exercise, 5 and 4 patients presented a reduction in systolic and diastolic BP of ≥4 mmHg, respectively. The clinical characteristics of the patients appear to influence BP responses after exercise. Individual data showed that some of the HIV+ women demonstrated a clinically significant decrease in BP. Although a single resistance exercise session does not decrease BP in women with HIV/AIDS, individual data present heterogeneity and individual characteristics seem to influence BP reduction after a single session of resistance exercises.

A confiabilidade do uso de recursos ergogênicos nutricionais no rendimento e na saúde do desportista parece ainda não ter alcançado consenso entre os especialistas da área. A prescrição indevida e a falta de informação do consumidor tem despertado preocupações sobre a utilização desse recurso em relação ao que promete oferecer e os eventos adversos que se manifestam. Este estudo se ocupa de uma revisão narrativa da leitura sobre a utilização de recursos ergogênicos nutricionais por desportistas. O artigo se estrutura em uma análise crítica e reflexiva da literatura, mediado por uma revisão tradicional da literatura. A seleção dos artigos, revisados e classificados como sustentação à escrita, foi arbitrária e com interferência da percepção subjetiva dos autores, assim como o método de estudo escolhido lhe permite. As informações foram obtidas por busca na base de dados do Google Acadêmico, Pubmed, SciELO, Lilacs e Medline. Os descritores utilizados foram: ergogênicos nutricionais e suplementação AND rendimento. Cuidados especiais no momento da escolha da suplementação ergogência são esperados, principalmente aqueles relacionados com o volume e a intensidade de esforço. São válidas as propostas de planos de nutrição desportiva inserido no meio atlético para possíveis esclarecimentos discriminação do uso de recursos ergogênicos nutricionais e ação individualizada no consumidor, além de programas continuados de promoção de saúde e prevenção de doenças, auxiliando no direcionamento das escolhas adotadas pelos esportistas e como garantir que os benefícios superem os possíveis efeitos colaterais negativos.

We evaluate the effect of a short-term supplementation with glutamine dipeptide (GluD) on the inflammatory and oxidative stress response to an acute session of resistance exercise in women living with HIV and using antiretroviral therapy (ART). Tenwomen diagnosed with HIV under ART were allocated in a randomized, double-blind, cross-over manner to receive 20 g/day of GluD or maltodextrin (placebo) supplementation for seven days with seven-days wash-out period. The participants performed an acute session of resistance training composed by seven exercises. Blood samples were taken before (pre), 1 hour and 2 hours after the exercise session for oxidative stress and inflammation markers determinations. Generalized estimating equations model, followed by the post-hoc Bonferroni test were used for statistical analysis. The resistance exercise session increased the concentrations of TNF-α, but the supplementation with GluD prevents this increase. Also, resistance exercise did not change plasma levels of IL-6.Regarding IL-10, there was a small reduction in both groups. For the oxidative stress markers, both conditions showed no change. A short period of GluD supplementation partially reduces the acute inflammatory response, caused by a session of resistance exercise, without altering the response of oxidative stress markers, in women living with HIV and using ART.