Abstract Objective:To investigate the accuracy of modified Risk of Malignancy Index (RMI) in predicting malignancy of epithelial type ovarian tumour. Method: This research was comparative research using cross-sectional study design, which compared RMI modification and RMI method in predicting malignancy of epithelial type ovarian tumour. The sampling technique was consecutive sampling. This research was conducted on October 2017 until samples were fulfilled in Obstetrics and Gynecology Division of RSUP Dr. M. Djamil and Laboratory of RSUP Dr. M Djamil in Padang. Chi-square test was used to compare specificity, sensitivity, positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio (PLR), negative likelihood ratio (NLR, and accuracy of RMI modification and RMI with 95% CI (p≤0,05). Results: A total of 61 subjects were recruited in this study. Sensitivity, specificity, PPV, NPV, PLR, NLR, and accuracy RMI modification scoring was 90.5%, 82.5%, 73.1%, 94.3%, 5.1, 0.1, dan 85.2%. Sensitivity, specificity, PPV, NPV, PLR, NLR, and accuracy RMI scoring was 66.7%, 70%, 53.8%, 80%, 2.2, 0.4, and 70% Conclusions:Modified RMI scoring method was more accurate in predicting the malignancy of ovarian type epithelial tumours than RMI. Keywords: CA125, malignancy, ovarian tumor,pelvic mass, RMI,   Abstrak Tujuan: Mengetahui akurasi Risk of Malignancy Index (RMI) dalam prediksi keganasan tumor ovarium tipe epitel.  Metode: Penelitian ini merupakan penelitian komparatif dengan desain penelitian potong lintang yang membandingkan metode RMI modifikasi dan RMI dalam prediksi keganasan tumor ovarium tipe epitel. Jumlah sampel sebanyak 61 orang. Teknik pengambilan sampel berurutan. Penelitian di mulai pada bulan Oktober 2017 hingga jumlah sampel terpenuhi di Departemen Obstetri dan Ginekologi RSUP Dr. M Djamil dan Laboratorium RSUP Dr. M Djamil Padang. Untuk membandingkan spesifisitas, sensitivitas, nilai duga positif (NDP), nilai duga negatif (NDN), rasio kemungkinan positif (RKP), rasio kemungkinan negatif (RKN), dan akurasi RMI modifikasi dan RMI digunakan uji chi-square dengan 99% CI (p≤0,01). Hasil: Sensitivitas, spesifisitas, NDP, NDN, RKP, RKN, dan akurasi skoring RMI modifikasi adalah 90,5%, 82,5%, 73,1%, 94,3%, 5,1, 0,1, dan 85,2%. Sensitivitas, spesifisitas, NDP, NDN, RKP, RKN, dan akurasi skoring RMI adalah 66,7%, 70%, 53,8%, 80%, 2,2, 0,4, dan 70%. Kesimpulan: Metode skoring RMI modifikasi lebih akurat dalam memprediksi keganasan tumor ovarium tipe epitel dibandingkan RMI. Kata kunci: CA125, keganasan, massapelvik, RMI, tumor ovarium

Postpartum blues occur in the first week after days 3-5 of labor, which occurs about 30%-80% in postpartum mothers. The purpose of this study was to determine the effectiveness of parenting counseling on postpartum blues incidence in the working area of Lubuk Buaya Community Health Center in 2017. The type of this research is Pre-Experiment conducted in the work area of Lubuk Buaya Puskesmas in 60 mothers of primigravida aterm (experimental and control group) selected by purposive sampling technique. The experimental group was given 1 time parenting counseling. All data were collected using questionnaires and data analyzed using the Wilcoxon test and Mann Whitney test, considered significant if p <0.05. The results of all respondents study age is not risky. The 37 weeks maternal gestational age categories in the experimental and control group were 73.3% and 63.3% and middle-level maternal education in the experimental and control group were 66.7% and 56.7%. With p-value<0,05, it means that parenting counseling done to mother and her husband is effective to increase mother's knowledge about parents readiness and there is difference / decrease of postpartum blues event. From the result of this study it can be conclude there is Parenting counseling performed on primigravida mothers is effective in improving maternal knowledge about parental readiness and there are differences in postpartum blues events between mothers given parenting counseling and those not given counseling.

Background: Anemia is an indirect cause of high maternal mortality rates worldwide characterized by low levels of hemoglobin, hepcidin, and serum ferritin. Hepcidin is a biomarker of iron metabolism in the body while ferritin acts as a store of iron. Hepcidin and ferritin levels during pregnancy will decrease. To restore the levels, supplementation is required either orally or intravenously. This study aimed to determine the effect of oral and intravenous iron supplementation on hepcidin and ferritin levels. Methods: This was an experimental laboratory study using Posttest Only Control Group Design. The sample was 24 Rattus Norvegicus divided into 4 groups: the negative control group without treatment, the positive control group given NaNo, the, P1 given oral iron supplementation, and the P2 given intravenous iron. The maintenance of the test animals in this study was carried out at the Pharmacy laboratory of Universitas Andalas Padang in June-August 2021. The experimental animals were Rattus Norvegicus Wistar females weighing 200-250 grams, aged between 3-4 months conditioned to be pregnant. The serum examination of hepcidin and ferritin levels used the ELISA method and the normality test used Shapiro Wilk. Then, the significance test used One-Way ANNOVA followed by multiple comparisons of Bonferroni types. Results: The results showed that there were significant differences (p<0.05) in hepcidin levels in the positive control group, treatment group 1, treatment 2 that were 219.52 ng/ml, 220.27 ng/ml, and 221.49 ng/ml. Likewise, the ferritin levels in the positive control group, treatment 1, and treatment 2 were 5.91 ng/ml, 6.81 ng/ml and 7.72 ng/ml. Conclusion: Based on the findings, it can be concluded that oral and intravenous iron supplementation had an effect on increasing serum hepcidin and ferritin levels in Rattus norvegicus pregnant strain Wistar with anemia. Keywords: Oral iron supplementation, intravenous supplementation, hepcidin and ferritin